This study will enroll 3,350 pregnant women during their first trimester, among whom a prospective nested case-control study of 300 gestational diabetes cases and 600 controls will be conducted to examine the association between early pregnancy levels of bisphenol-A (BPA) and the risk of GDM in the second trimester, as well as the association between BPA and high levels of metabolic markers of insulin resistance and liver enzymes, and the risk of having a large for gestational age (LGA) infant.
Prenatal Bisphenol A Exposure and Risk of Gestational Diabetes
Investigator: Ferrara, Assiamira
Funder: National Institute of Environmental Health Sciences