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Comparative effectiveness of intermittently scanned continuous glucose monitors among patients with basal-bolus insulin-treated type 2 diabetes

This study will characterize patients selected by their providers for intermittently-scanned, continuous glucose monitor (isCGM) initiation and estimate the effect of isCGM initiation (relative to non-initiators) on clinical outcomes. We hypothesize that 1) among basal-bolus insulin treated, type 2 diabetes patients, those with poorer glycemic control and history of acute metabolic events are more likely selected by physicians for isCGM initiation, and 2) isCGM initiation will result in significant improvement in glycemic control (based on hemoglobin A1c), reduced risk of hypoglycemia and hyperglycemia (both based on emergency department or hospital utilization), compared with non-initiators. This comparative effectiveness research will be based on a difference-in-differences analysis of changes in these outcomes associated with isCGM initiation, compared to a reference group of patients who do not use isCGM (usual care).
Investigator: Karter, Andrew
Funder: TPMG Delivery Science Projects Program