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Characterizing the Risk of Chemotherapy Side Effects Based on Epigenetic Age and Modification by Resistance Training Intervention

This study is investigating whether an individual's epigenetic age — a molecular marker of biological age — at the start of chemotherapy is associated with chemotoxicity in patients receiving treatment for colon cancer and whether resistance training during chemotherapy attenuates that association. We will also investigate if chemotherapy changes these patients' epigenetic age and whether resistance training attenuates those changes.
Investigator: Caan, Bette
Funder: National Cancer Institute