Many patients with blood clots can go home from ER
A decision support tool implemented in Kaiser Permanente Northern California emergency departments in 2016 has continued to help physicians safely discharge patients with an acute pulmonary embolism to their homes without harmful effects, a new study shows.
David Baer, MD: A passion for cancer research
David Baer, MD, cofounded the KP Oncology Clinical Trials program in the 1980s. He has enrolled significant numbers of patients in these trials, and helped expand the regional effort into a national KP program. As a leading member of the Northern California Central Research Committee for most of his career, he provides valuable experience in the practicality of research within Kaiser Permanente.
More metastatic prostate cancers found after change in screening guidelines
In the years after the U.S. Preventive Services Task Force recommended against PSA-based screening in all men, many fewer men were diagnosed with prostate cancer but more were found to have advanced cancers, according to a large Kaiser Permanente study published today in the Journal of General Internal Medicine.
Body fatness affects chemo dosages, contributing to increased risk of breast cancer death
Women with greater adiposity, or body fatness, were significantly less likely to receive all of the recommended chemotherapy dose to treat their breast cancer, and they were subsequently 30% more likely to die from the disease as a result, according to research published in JAMA Oncology.
Use of insulin among older adults with type 2 diabetes not aligned with national guidelines
Listen on KP RESEARCH RADIO:
“What we learned is that contrary to recommendations from leading societies, sicker patients were more likely to be on insulin, and over time were less likely to be discontinued from their insulin.”
– Dr. Richard Grant, senior author of study in JAMA Internal Medicine.
Teen bedtime and sleeping patterns can influence risk of obesity and poor cardiometabolic health
Adolescent sleep timing preferences and patterns should be considered risk factors for obesity and cardiometabolic health, according to a new study by researchers with the Kaiser Permanente Division of Research and Massachusetts General Hospital.
Kaiser Permanente research shows mastectomy patients recover safely at home
A study in Annals of Surgical Oncology finds that the rate of home recovery after mastectomy increased from 23% regionwide to 61% in the 6 months after the program started, with no significant changes in emergency-department visits, reoperations, or readmissions.
Use of CT scans during pregnancy increased in U.S. and Canada over 2 decades
A large, multicenter study of advanced medical imaging in pregnancy, published in JAMA Network Open and co-led by Marilyn Kwan, PhD, found that CT scans were performed in 0.8% of pregnancies in the United States and 0.4% in Ontario in 2016; these rates increased nearly fourfold in the United States and doubled in Ontario over the 21 years.
New study finds both components of blood pressure predict heart attack, stroke risk
“This research brings a large amount of data to bear on a basic question, and it gives such a clear answer,” said lead author Alexander C. Flint, MD, PhD, Kaiser Permanente stroke specialist and adjunct researcher with the Division of Research. “Every way you slice the data, the systolic and diastolic pressures are both important.”
Clinical tool accurately predicts children’s appendicitis risk in Kaiser Permanente emergency rooms
Erring on the side of caution, emergency physicians tend to order CT scans to evaluate appendicitis in children, “but research shows that we weren’t necessarily catching more appendicitis,” Dr. Cotton said. “CT scans are costly and expose children to ionizing radiation that can increase the risk of cancer. At the same time, emergency physicians do not want to miss an important diagnosis like appendicitis.”
Pregnancy history of red-blood-cell donors not linked to higher mortality in transfusion recipients
Division of Research investigators participated in a multi-institution collaborative analysis, which supported the safety of current transfusion practice within Kaiser Permanente’s network of community hospitals.
Mother’s pregnancy weight linked to early puberty in daughters
A Kaiser Permanente study of more than 2,000 mothers and daughters found that the amount of weight mothers gained during pregnancy — whether too much or too little — was linked to the earlier onset of puberty in their daughters; the associations were even stronger when the mothers were overweight or obese at the beginning of the pregnancy.
New study data suggests revising heart disease management guidelines for colon cancer survivors
“This study demonstrates the importance at every BMI level of having more precise measures of muscle and fat to help identify those patients who are at high risk of developing cardiovascular disease,” said co-author Bette J. Caan, DrPH.
Video visits convenient and high quality, Kaiser Permanente members say
Nine out of 10 Kaiser Permanente members who had a primary-care video visit were confident in the quality of care received, reported that the provider was familiar with their medical history, and felt that their health care needs were adequately addressed.
Temperament of Babies Born to Mothers with Diabetes During Pregnancy Linked to Childhood Obesity
Kaiser Permanente prospective study finds that easier-to-soothe babies were more likely to be obese by age 5, and more likely to have started drinking sugared beverages during the first 6 months of life.
Kaiser Permanente Study Finds 10-Year Follow-up Interval After Negative Colonoscopies Is Associated with Reduced Risk of Colorectal Cancer and Mortality
Ten years after a negative colonoscopy, Kaiser Permanente members had 46 percent lower risk of being diagnosed with and were 88 percent less likely to die from colorectal cancer compared with those who did not undergo colorectal cancer screening.
Kaiser Permanente “Tele-triage” of Chest Pain Safely Reduces Emergency Room Visits
A new Kaiser Permanente study led by Dana Sax, MD, published today in the December issue of the journal Health Affairs, found that “tele-triage” of patients with chest pain over the phone can safely and effectively direct people to the right place for receiving care.
Delivering the Next Generation of Diabetes Scientists
The Kaiser Permanente Division of Research has received a T32 grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to train young scientists in translating research into practice for people with type 2 diabetes and prediabetes.
5 Questions for… Steve Sidney
“If other health care systems and providers had adopted Kaiser Permanente’s approach and achieved the same rate of decline, I estimated in this latest National Forum report that 40,000 heart disease and stroke deaths in this age group would have been prevented in 2015 alone.”
A Better Way to Assess Ovarian Cancer Risk
New radiology guidelines developed by Kaiser Permanente gynocological oncologist and researcher Betty Suh-Burgman, MD, allow women at higher risk for ovarian cancer to be promptly referred for surgical evaluation while women at low risk can safely avoid surgery.
Study Finds Wide Variations in Projected Heart Benefits of Anti-Blood-Clotting Medications for People with Atrial Fibrillation
The reported rates of ischemic stroke in four large studies vary substantially, creating uncertainty about the predicted benefits of anticoagulation medication, according to new findings in Annals of Internal Medicine by Kaiser Permanente researchers and colleagues.
Integrated Colorectal Cancer Screening Program Saves Lives
Kaiser Permanente members in Northern California are 52 percent less likely to die from colorectal cancer since the health care system launched a comprehensive, organized screening program, according to a new study in the specialty’s top journal, Gastroenterology.
Partners of Newly Diagnosed Diabetes Patients More Likely to Adopt Healthy Behaviors
Partners of people with newly diagnosed diabetes are more likely to improve their health behaviors than partners of people without the disease, according to a large new Kaiser Permanente study published today in Annals of Family Medicine.
Division of Research’s Theodore Levin, MD, honored for colorectal cancer screening program
DOR’s Theodore (TR) Levin, MD, is one of four recipients of The Permanente Medical Group’s 2018 Sidney R. Garfield Exceptional Contribution Awards, for pioneering efforts to expand colorectal cancer screening.
Personalized Letter Improves Pregnancy Weight for Women with Gestational Diabetes
Women with gestational diabetes who received a tailored letter with personalized weight-gain recommendations were significantly more likely to meet national weight-gain guidelines, according to a Kaiser Permanente study published in Diabetes Care.
In Reducing Deaths from Heart Disease and Stroke, Kaiser Permanente Outpaces Nation
Death rates from heart disease and stroke in adults under age 65 are lower and dropping faster for Kaiser Permanente members in Northern California than in the rest of the United States, according to new research published today in the American Journal of Medicine.
Integrated Program Improves Heart and Stroke Risk Factors in Those With Diabetes
Over a 10-year period, control of three key cardiovascular risk factors improved faster for Kaiser Permanente diabetes patients in Northern California than in the rest of the United States, according to research published in the American Journal of Medicine.
A Heart-to-Heart for Researchers
The second Cardiovascular Research Symposium drew approximately 80 people including researchers, sub-specialty physicians, quality and operational staff, and others from across Kaiser Permanente’s Northern California region. It was convened at the Division of Research (DOR) in Oakland by Alan S. Go, MD, DOR’s associate director of Cardiovascular and Metabolic Conditions Research.
New Kaiser Permanente Study Reveals an Increase in Marijuana Use During Pregnancy
A new study from the Division of Research, using data from almost 300,000 pregnant women treated at Kaiser Permanente Northern California, found that maternal prenatal marijuana use increased from 4 to 7 percent from 2009 to 2016.
DOR’s Steve Sidney honored by National Forum for “exceptional contributions,” research on U.S. heart disease trends
The Division of Research’s Stephen Sidney, MD, MPH was honored by the National Forum for Heart Disease and Stroke Prevention for his “exceptional contributions” as well as his work on understanding national trends in cardiovascular disease.
Physician researchers build bridges to health care innovation
David Vinson, MD, has been conducting research on nights and weekends for much of his 17-year career as an emergency-room physician in The Permanente Medical Group. A new program sponsored by TPMG will allow him to dedicate a portion of his clinical work week to research, while collaborating with investigators at the Division of Research.
Translating Research Into Improved Women’s Health Care
Elizabeth “Betty” Suh-Burgmann, MD, says her latest research project was “born out of frustration with the state of affairs” for managing adnexal masses in women. Like gynecological oncologists across the nation, she saw many women at her Kaiser Permanente Walnut Creek practice undergo surgeries to determine whether small masses in their ovaries were benign or cancerous.
Edmund (Ted) Van Brunt, former Kaiser Permanente research director and pioneer of electronic health records, dies at age 91
Edmund (Ted) Van Brunt, MD, former director of the Kaiser Permanente Division of Research and a pioneer in the use of electronic health records in medical science, died at his home in Berkeley on May 19, 2017. He was 91 years old.