DOR contributes to understanding of perinatal exposures to a variety of factors, from environmental chemicals to maternal depression. Key findings include:
- associations between excessive gestational weight gain and severe neonatal complications,
- maternal infections, rather than use of antibiotics, during pregnancy were associated with increased risk of obesity in offspring,
- associations between maternal infection, fever, autoimmune disease, inflammation and other immune conditions during pregnancy and the risk of autism spectrum disorders in children.
Also, our investigators are examining the risk of neurodevelopment disorders associated with in-utero exposure to maternal inflammation and use of antidepressants, and potential effects of maternal exposure to environmental chemicals such as PFAS on children’s developmental outcomes.