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Alison Fohner, PhD, is an Adjunct Investigator specializing in clinical informatics at the Kaiser Permanente Northern California Division of Research. Her work combines highly granular electronic health record data with genetic data to identify predictors of outcome and drug response among hospitalized patients, with the goal of implementing electronic decision support to improve personalized medicine in acute care. She also is studying the implementation of preemptive pharmacogenetic testing.

Dr. Fohner holds bachelor’s and master’s degrees in biology from Stanford University, and a PhD in public health genetics from the University of Washington. Her doctoral work focused on genetic and environmental predictors of drug response and health outcomes in American Indian and Alaska Native communities.

Publications

Assessing clinical heterogeneity in sepsis through treatment patterns and machine learning

Authors: Fohner AE; Greene JD; Lawson BL; Chen JH; Kipnis P; Escobar GJ; Liu VX

J Am Med Inform Assoc. 2019 12 01;26(12):1466-1477.

PubMed abstract

Assessing the clinical impact of CYP2C9 pharmacogenetic variation on phenytoin prescribing practice and patient response in an integrated health system

Authors: Fohner AE; Ranatunga DK; Thai KK; Lawson BL; Risch N; Oni-Orisan A; Jelalian AT; Rettie AE; Liu VX; Schaefer CA

Pharmacogenet Genomics. 2019 10;29(8):192-199.

PubMed abstract

​Carnitine palmitoyltransferase 1A P479L and infant death: policy implications of emerging data.

Authors: Fohner AE; Garrison NA; ,; Austin MA; Burke W;

​Genet Med. 2017 Aug;19(8):851-857. doi: 10.1038/gim.2016.202. Epub 2017 Jan 26.

PubMed abstract

​Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup’ik Study Population from Southwestern Alaska.

Authors: Fohner AE; Wang Z; Yracheta J; O'Brien DM; Hopkins SE; Black J; Philip J; Wiener HW; Tiwari HK; Stapleton PL; Tsai JM; Thornton TA; Boyer BB; Thummel KE

​J Nutr. 2016 Feb;146(2):318-25. doi: 10.3945/jn.115.223388. Epub 2015 Dec 9.

PubMed abstract

​Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX.

Authors: Fohner AE; Robinson R; Yracheta J; Dillard DA; Schilling B; Khan B; Hopkins S; Boyer B; Black J; Wiener H; Tiwari HK; Gordon A; Nickerson D; Tsai JM; Farin FM; Thornton TA; Rettie AE; Thummel KE

​Pharmacogenet Genomics. 2015 Jul;25(7):343-353. doi: 10.1097/FPC.0000000000000143.

PubMed abstract

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