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Nareg H. Roubinian, MD, MPH

Kaiser Permanente Researcher Profiles

Roubinian, Nareg

Publications

The prevalence of hepatitis B virus, human T-lymphotropic virus and human immunodeficiency virus in patients receiving blood transfusions in South Africa

Authors: Willemse, Reynier J;Grobler, Christa J;Murphy, Edward L;Roubinian, Nareg;Colemen, Charl;Machaba, Solly;Vermeulen, Marion

Vox Sang. 2024 Sep 11.

PubMed abstract

Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes

Authors: Nemkov, Travis;Roubinian, Nareg;D'Alessandro, Angelo;et al.

Cell Metab. 2024 Sep 03;36(9):1979-1997.e13. Epub 2024-07-03.

PubMed abstract

Expanding outpatient management of low-risk pulmonary embolism to the pregnant population: a case series

Authors: Vinson, David R;Roubinian, Nareg H;Pai, Ashok P;Sperling, Jeffrey D

Eur Heart J Case Rep. 2024 Sep;8(9):ytae441. Epub 2024-08-22.

PubMed abstract

Testosterone supplementation increases red blood cell susceptibility to oxidative stress, decreases membrane deformability, and decreases survival after cold storage and transfusion

Authors: Tran, Johnson;Roubinian, Nareg H;Kanias, Tamir;et al.

Transfusion. 2024 Jun 17.

PubMed abstract

Hospital-associated venous thromboembolism prophylaxis use by risk assessment at a large integrated health care network in Northern California

Authors: Xu, James;Neeman, Elad;Thai, Khanh K;Mishra, Pranita;Schlessinger, David;Clancy, Heather;Myers, Laura;Roubinian, Nareg;Liu, Vincent;Liu, Raymond

J Hosp Med. 2024 Jun;19(6):449-459. Epub 2024-04-12.

PubMed abstract

Video-Assisted vs Robotic-Assisted Lung Lobectomies for Operating Room Resource Utilization and Patient Outcomes

Authors: Tupper, Haley I;Lawson, Brian L;Kipnis, Patricia;Patel, Ashish R;Ashiku, Simon K;Roubinian, Nareg H;Myers, Laura C;Liu, Vincent X;Velotta, Jeffrey B

JAMA Netw Open. 2024 May 01;7(5):e248881. Epub 2024-05-01.

PubMed abstract

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo

Authors: Nemkov, Travis;Roubinian, Nareg H;D'Alessandro, Angelo;et al.

Blood. 2024 Feb 01;143(5):456-472.

PubMed abstract

Clinical outcomes in hospitalized plasma and platelet transfusion recipients prior to and following widespread blood donor SARS-CoV-2 infection and vaccination

Authors: Roubinian, Nareg H;Liu, Vincent X;Lee, Catherine;Mark, Dustin G;Vinson, David R;NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV),;et al.

Transfusion. 2024 Jan;64(1):53-67. Epub 2023-12-06.

PubMed abstract

Selected Topics From the State of the Science in Transfusion Medicine: Key Insights on Current Progress and Future Directions

Authors: Roubinian, Nareg H;Custer, Brian

Transfus Med Rev. 2023 Oct;37(4):150781. Epub 2023-11-01.

PubMed abstract

The impact of timing of initiating invasive mechanical ventilation in COVID-19-related respiratory failure

Authors: Myers, Laura C;Kipnis, Patricia;Greene, John D;Chen, Aiyu;Creekmur, Beth;Xu, Stan;Sankar, Viji;Roubinian, Nareg H;Langer-Gould, Annette;Gould, Michael K;Liu, Vincent X

J Crit Care. 2023 Oct;77:154322. Epub 2023-05-08.

PubMed abstract

Associations of donor, component, and recipient factors on hemoglobin increments following red blood cell transfusion in very low birth weight infants

Authors: DeSimone, Robert A;Plimier, Colleen;Goel, Ruchika;Hendrickson, Jeanne E;Josephson, Cassandra D;Patel, Ravi M;Sola-Visner, Martha;Roubinian, Nareg H

Transfusion. 2023 Aug;63(8):1424-1429. Epub 2023-06-30.

PubMed abstract

Letter to the editor: “Clinical controversies in the management of acute pulmonary embolism”

Authors: Casey, Scott D;Rouleau, Samuel G;Vinson, David R;Roubinian, Nareg H

Expert Rev Respir Med. 2023 May 18:1-2.

PubMed abstract

Disentangling the causes of RBC loss and anemia in ECMO patients: Some questions answered?

Authors: Goel, Ruchika;Roubinian, Nareg H;Bembea, Melania M

Transfusion. 2023 May;63(5):899-902. Epub 2023-04-10.

PubMed abstract

Acute myocardial infarction and blood transfusion: lessons learned from animal models and clinical studies

Authors: Roubinian, Nareg H;Carson, Jeffrey L

Blood Transfus. 2023 May;21(3):185-188.

PubMed abstract

Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium

Authors: Custer, Brian;Glynn, Simone A;Roubinian, Nareg H;et al.

Transfusion. 2023 May;63(5):1074-1091. Epub 2023-04-02.

PubMed abstract

Blood donor, component, and recipient-specific factors associated with venous thromboembolism in transfused hospitalized adult patients: Data from the recipient epidemiology and donor evaluation Study-III (REDS-III)

Authors: Goel, Ruchika; Plimier, Colleen; Lee, Catherine; Tobian, Aaron A R; Josephson, Cassandra D; Hod, Eldad A; Roubinian, Nareg H

Transfusion. 2023 May;63(5):925-932. Epub 2023-02-25.

PubMed abstract

Review of Pulmonary Embolism

Authors: Vinson, David R; Sperling, Jeffrey D; Roubinian, Nareg H

JAMA. 2023 Feb 21;329(7):593.

PubMed abstract

Risk of venous thromboembolism in non-respiratory and respiratory presentations of COVID-19 in critically ill patients

Authors: Roubinian, Nareg H; Vinson, David R; Pai, Ashok P; Myers, Laura C; Skarbinski, Jacek; Lee, Catherine; Mark, Dustin G; Liu, Vincent X

Chest. 2023 Feb 12.

PubMed abstract

Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status

Authors: Roubinian, Nareg H;Vinson, David R;Knudson-Fitzpatrick, Tess Wheeler;Mark, Dustin G;Skarbinski, Jacek;Lee, Catherine;Liu, Vincent X;Pai, Ashok P

Blood Adv. 2023 Jan 10;7(1):141-144.

PubMed abstract

Association between anaemia and hospital readmissions in patients undergoing major surgery requiring postoperative intensive care

Authors: Warner, M A; Hanson, A C; Plimier, C; Lee, C; Liu, V X; Richards, T; Kor, D J; Roubinian, N H

Anaesthesia. 2023 Jan;78(1):45-54. Epub 2022-09-08.

PubMed abstract

Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection

Authors: van den Berg, Karin; Roubinian, Nareg; On Behalf Of The Recipient Epidemiology And Donor Evaluation Study Reds-Iii South Africa International Program,; et al.

Viruses. 2022 Oct 23;14(11). Epub 2022-10-23.

PubMed abstract

Early Post-Hospitalization Hemoglobin Recovery and Clinical Outcomes in Survivors of Critical Illness: A Population-Based Cohort Study

Authors: Warner, Matthew A; Hanson, Andrew C; Schulte, Phillip J; Roubinian, Nareg H; Storlie, Curt; Demuth, Gabriel; Gajic, Ognjen; Kor, Daryl J

J Intensive Care Med. 2022 Aug;37(8):1067-1074. Epub 2022-02-01.

PubMed abstract

Red Blood Cell Transfusion at a Hemoglobin Threshold of Seven g/dL in Critically Ill Patients: A Regression Discontinuity Study

Authors: Bosch, Nicholas A; Law, Anica C; Bor, Jacob; Myers, Laura C; Roubinian, Nareg H; Liu, Vincent X; Walkey, Allan J

Ann Am Thorac Soc. 2022 07;19(7):1177-1184.

PubMed abstract

Donor genetic and non-genetic factors affecting red blood cell transfusion effectiveness

Authors: Roubinian, Nareg H; Hod, Eldad A; et al.

JCI Insight. 2022 01 11;7(1). Epub 2022-01-11.

PubMed abstract

Transfusion thresholds for guiding red blood cell transfusion

Authors: Carson, Jeffrey L; Stanworth, Simon J; Dennis, Jane A; Trivella, Marialena; Roubinian, Nareg; Fergusson, Dean A; Triulzi, Darrell; Dorée, Carolyn; Hébert, Paul C

Cochrane Database Syst Rev. 2021 12 21;12:CD002042. Epub 2021-12-21.

PubMed abstract

Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress

Authors: Hazegh, Kelsey; Bertolone, Lorenzo; Kanias, Tamir; et al.

Transfusion. 2021 02;61(2):435-448. Epub 2020-11-04.

PubMed abstract

NT-proBNP levels in the identification and classification of pulmonary transfusion reactions

Authors: Roubinian, Nareg H; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III),; et al.

Transfusion. 2020 11;60(11):2548-2556. Epub 2020-09-09.

PubMed abstract

Red blood cell transfusions for emergency department patients with gastrointestinal bleeding within an integrated health system

Authors: Mark DG; Huang J; Plimier C; Reed ME; Escobar GJ; Vinson DR; Roubinian NH

Am J Emerg Med. 2020 04;38(4):746-753. Epub 2019-06-10.

PubMed abstract

Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting

Authors: Bloch EM; Roubinian N; NHLBI REDS-III South Africa Program; et al.

Transfusion. 2020 03;60(3):479-487. Epub 2020-01-07.

PubMed abstract

Methodological considerations for linked blood donor-component-recipient analyses in transfusion medicine research

Authors: Roubinian N; Kleinman S; Murphy EL; Glynn SA; Edgren G

ISBT Sci Ser. 2020 Feb;15(1):185-193. Epub 2019-08-28.

PubMed abstract

Equivalent inpatient mortality among direct-acting oral anticoagulant and warfarin users presenting with major hemorrhage

Authors: Bialkowski W; Roubinian N; NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study; et al.

Thromb Res. 2020 01;185:109-118. Epub 2019-11-25.

PubMed abstract

Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients

Authors: Roubinian NH; Lee C; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III); et al.

Transfusion. 2019 11;59(11):3362-3370. Epub 2019-10-11.

PubMed abstract

Transfusion-Associated Circulatory Overload and Transfusion-Related Acute Lung Injury: Etiology and Prevention

Authors: Roubinian NH; Triulzi DJ

Hematol Oncol Clin North Am. 2019 10;33(5):767-779. Epub 2019-07-30.

PubMed abstract

Effect of donor, component and recipient characteristics on hemoglobin increments following red blood cell transfusion

Authors: Roubinian NH; Plimier C; Woo JP; Lee C; Bruhn R; Liu VX; Escobar GJ; Kleinman SH; Triulzi DJ; Murphy EL; Busch MP

Blood. 2019 09 26;134(13):1003-1013. Epub 2019-07-26.

PubMed abstract

Blood donor component-recipient linkages: is there fire where there is smoke?

Authors: Roubinian NH; Kanias T

Transfusion. 2019 08;59(8):2485-2488.

PubMed abstract

The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases

Authors: Karafin MS; Roubinian NH; NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study; et al.

Transfusion. 2019 08;59(8):2544-2550. Epub 2019-07-04.

PubMed abstract

Building consensus: steps toward standardised haemovigilance reporting

Authors: Roubinian N; Kleinman S

Lancet Haematol. 2019 07;6(7):e339-e340. Epub 2019-05-09.

PubMed abstract

Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients

Authors: Edgren G; Lee C; Roubinian NH; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Group; et al.

JAMA. 2019 06 11;321(22):2183-2192.

PubMed abstract

Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study

Authors: Roubinian NH; Murphy EL; Mark DG; Triulzi DJ; Carson JL; Lee C; Kipnis P; Kleinman S; Liu VX; Escobar GJ

Ann Intern Med. 2019 01 01;170(1):80.

PubMed abstract

TACO and TRALI: biology, risk factors, and prevention strategies

Authors: Roubinian N

Hosp Pediatr. 2019 05;9(5):340-347.

PubMed abstract

Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload

Authors: Roubinian NH; National Heart, Lung, and Blood Institute (NHLBI) Recipient Epidemiology and Donor Evaluation Study-III (REDS-III); et al.

Crit Care Med. 2018 04;46(4):577-585.

PubMed abstract

Statistical Caution in Big Data Approaches to Transfusion Medicine Research

Authors: Roubinian N; Brambilla D; Murphy EL

JAMA Intern Med. 2017 06 01;177(6):860-861.

PubMed abstract

Adjusting the Focus on Transfusion-associated Circulatory Overload

Authors: Roubinian N; Murphy EL

Anesthesiology. 2017 03;126(3):363-365.

PubMed abstract

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