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Nareg H. Roubinian, MD, MPH

Kaiser Permanente Researcher Profiles

Roubinian, Nareg

Publications

Testosterone supplementation increases red blood cell susceptibility to oxidative stress, decreases membrane deformability, and decreases survival after cold storage and transfusion

Authors: Tran, Johnson;Roubinian, Nareg H;Kanias, Tamir;et al.

Transfusion. 2024 Jun 17.

PubMed abstract

Hospital-associated venous thromboembolism prophylaxis use by risk assessment at a large integrated health care network in Northern California

Authors: Xu, James;Neeman, Elad;Thai, Khanh K;Mishra, Pranita;Schlessinger, David;Clancy, Heather;Myers, Laura;Roubinian, Nareg;Liu, Vincent;Liu, Raymond

J Hosp Med. 2024 Jun;19(6):449-459. Epub 2024-04-12.

PubMed abstract

Video-Assisted vs Robotic-Assisted Lung Lobectomies for Operating Room Resource Utilization and Patient Outcomes

Authors: Tupper, Haley I;Lawson, Brian L;Kipnis, Patricia;Patel, Ashish R;Ashiku, Simon K;Roubinian, Nareg H;Myers, Laura C;Liu, Vincent X;Velotta, Jeffrey B

JAMA Netw Open. 2024 May 01;7(5):e248881. Epub 2024-05-01.

PubMed abstract

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo

Authors: Nemkov, Travis;Roubinian, Nareg H;D'Alessandro, Angelo;et al.

Blood. 2024 Feb 01;143(5):456-472.

PubMed abstract

Clinical outcomes in hospitalized plasma and platelet transfusion recipients prior to and following widespread blood donor SARS-CoV-2 infection and vaccination

Authors: Roubinian, Nareg H;Liu, Vincent X;Lee, Catherine;Mark, Dustin G;Vinson, David R;NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV),;et al.

Transfusion. 2024 Jan;64(1):53-67. Epub 2023-12-06.

PubMed abstract

Selected Topics From the State of the Science in Transfusion Medicine: Key Insights on Current Progress and Future Directions

Authors: Roubinian, Nareg H;Custer, Brian

Transfus Med Rev. 2023 Oct;37(4):150781. Epub 2023-11-01.

PubMed abstract

The impact of timing of initiating invasive mechanical ventilation in COVID-19-related respiratory failure

Authors: Myers, Laura C;Kipnis, Patricia;Greene, John D;Chen, Aiyu;Creekmur, Beth;Xu, Stan;Sankar, Viji;Roubinian, Nareg H;Langer-Gould, Annette;Gould, Michael K;Liu, Vincent X

J Crit Care. 2023 Oct;77:154322. Epub 2023-05-08.

PubMed abstract

Associations of donor, component, and recipient factors on hemoglobin increments following red blood cell transfusion in very low birth weight infants

Authors: DeSimone, Robert A;Plimier, Colleen;Goel, Ruchika;Hendrickson, Jeanne E;Josephson, Cassandra D;Patel, Ravi M;Sola-Visner, Martha;Roubinian, Nareg H

Transfusion. 2023 Aug;63(8):1424-1429. Epub 2023-06-30.

PubMed abstract

Letter to the editor: “Clinical controversies in the management of acute pulmonary embolism”

Authors: Casey, Scott D;Rouleau, Samuel G;Vinson, David R;Roubinian, Nareg H

Expert Rev Respir Med. 2023 May 18:1-2.

PubMed abstract

Disentangling the causes of RBC loss and anemia in ECMO patients: Some questions answered?

Authors: Goel, Ruchika;Roubinian, Nareg H;Bembea, Melania M

Transfusion. 2023 May;63(5):899-902. Epub 2023-04-10.

PubMed abstract

Acute myocardial infarction and blood transfusion: lessons learned from animal models and clinical studies

Authors: Roubinian, Nareg H;Carson, Jeffrey L

Blood Transfus. 2023 May;21(3):185-188.

PubMed abstract

Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium

Authors: Custer, Brian;Glynn, Simone A;Roubinian, Nareg H;et al.

Transfusion. 2023 May;63(5):1074-1091. Epub 2023-04-02.

PubMed abstract

Blood donor, component, and recipient-specific factors associated with venous thromboembolism in transfused hospitalized adult patients: Data from the recipient epidemiology and donor evaluation Study-III (REDS-III)

Authors: Goel, Ruchika; Plimier, Colleen; Lee, Catherine; Tobian, Aaron A R; Josephson, Cassandra D; Hod, Eldad A; Roubinian, Nareg H

Transfusion. 2023 May;63(5):925-932. Epub 2023-02-25.

PubMed abstract

Review of Pulmonary Embolism

Authors: Vinson, David R; Sperling, Jeffrey D; Roubinian, Nareg H

JAMA. 2023 Feb 21;329(7):593.

PubMed abstract

Risk of venous thromboembolism in non-respiratory and respiratory presentations of COVID-19 in critically ill patients

Authors: Roubinian, Nareg H; Vinson, David R; Pai, Ashok P; Myers, Laura C; Skarbinski, Jacek; Lee, Catherine; Mark, Dustin G; Liu, Vincent X

Chest. 2023 Feb 12.

PubMed abstract

Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status

Authors: Roubinian, Nareg H;Vinson, David R;Knudson-Fitzpatrick, Tess Wheeler;Mark, Dustin G;Skarbinski, Jacek;Lee, Catherine;Liu, Vincent X;Pai, Ashok P

Blood Adv. 2023 Jan 10;7(1):141-144.

PubMed abstract

Association between anaemia and hospital readmissions in patients undergoing major surgery requiring postoperative intensive care

Authors: Warner, M A; Hanson, A C; Plimier, C; Lee, C; Liu, V X; Richards, T; Kor, D J; Roubinian, N H

Anaesthesia. 2023 Jan;78(1):45-54. Epub 2022-09-08.

PubMed abstract

Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection

Authors: van den Berg, Karin; Roubinian, Nareg; On Behalf Of The Recipient Epidemiology And Donor Evaluation Study Reds-Iii South Africa International Program,; et al.

Viruses. 2022 Oct 23;14(11). Epub 2022-10-23.

PubMed abstract

Early Post-Hospitalization Hemoglobin Recovery and Clinical Outcomes in Survivors of Critical Illness: A Population-Based Cohort Study

Authors: Warner, Matthew A; Hanson, Andrew C; Schulte, Phillip J; Roubinian, Nareg H; Storlie, Curt; Demuth, Gabriel; Gajic, Ognjen; Kor, Daryl J

J Intensive Care Med. 2022 Aug;37(8):1067-1074. Epub 2022-02-01.

PubMed abstract

Red Blood Cell Transfusion at a Hemoglobin Threshold of Seven g/dL in Critically Ill Patients: A Regression Discontinuity Study

Authors: Bosch, Nicholas A; Law, Anica C; Bor, Jacob; Myers, Laura C; Roubinian, Nareg H; Liu, Vincent X; Walkey, Allan J

Ann Am Thorac Soc. 2022 07;19(7):1177-1184.

PubMed abstract

Donor genetic and non-genetic factors affecting red blood cell transfusion effectiveness

Authors: Roubinian, Nareg H; Hod, Eldad A; et al.

JCI Insight. 2022 01 11;7(1). Epub 2022-01-11.

PubMed abstract

Transfusion thresholds for guiding red blood cell transfusion

Authors: Carson, Jeffrey L; Stanworth, Simon J; Dennis, Jane A; Trivella, Marialena; Roubinian, Nareg; Fergusson, Dean A; Triulzi, Darrell; Dorée, Carolyn; Hébert, Paul C

Cochrane Database Syst Rev. 2021 12 21;12:CD002042. Epub 2021-12-21.

PubMed abstract

Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress

Authors: Hazegh, Kelsey; Bertolone, Lorenzo; Kanias, Tamir; et al.

Transfusion. 2021 02;61(2):435-448. Epub 2020-11-04.

PubMed abstract

NT-proBNP levels in the identification and classification of pulmonary transfusion reactions

Authors: Roubinian, Nareg H; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III),; et al.

Transfusion. 2020 11;60(11):2548-2556. Epub 2020-09-09.

PubMed abstract

Red blood cell transfusions for emergency department patients with gastrointestinal bleeding within an integrated health system

Authors: Mark DG; Huang J; Plimier C; Reed ME; Escobar GJ; Vinson DR; Roubinian NH

Am J Emerg Med. 2020 04;38(4):746-753. Epub 2019-06-10.

PubMed abstract

Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting

Authors: Bloch EM; Roubinian N; NHLBI REDS-III South Africa Program; et al.

Transfusion. 2020 03;60(3):479-487. Epub 2020-01-07.

PubMed abstract

Methodological considerations for linked blood donor-component-recipient analyses in transfusion medicine research

Authors: Roubinian N; Kleinman S; Murphy EL; Glynn SA; Edgren G

ISBT Sci Ser. 2020 Feb;15(1):185-193. Epub 2019-08-28.

PubMed abstract

Equivalent inpatient mortality among direct-acting oral anticoagulant and warfarin users presenting with major hemorrhage

Authors: Bialkowski W; Roubinian N; NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study; et al.

Thromb Res. 2020 01;185:109-118. Epub 2019-11-25.

PubMed abstract

Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients

Authors: Roubinian NH; Lee C; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III); et al.

Transfusion. 2019 11;59(11):3362-3370. Epub 2019-10-11.

PubMed abstract

Transfusion-Associated Circulatory Overload and Transfusion-Related Acute Lung Injury: Etiology and Prevention

Authors: Roubinian NH; Triulzi DJ

Hematol Oncol Clin North Am. 2019 10;33(5):767-779. Epub 2019-07-30.

PubMed abstract

Effect of donor, component and recipient characteristics on hemoglobin increments following red blood cell transfusion

Authors: Roubinian NH; Plimier C; Woo JP; Lee C; Bruhn R; Liu VX; Escobar GJ; Kleinman SH; Triulzi DJ; Murphy EL; Busch MP

Blood. 2019 09 26;134(13):1003-1013. Epub 2019-07-26.

PubMed abstract

The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases

Authors: Karafin MS; Roubinian NH; NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study; et al.

Transfusion. 2019 08;59(8):2544-2550. Epub 2019-07-04.

PubMed abstract

Blood donor component-recipient linkages: is there fire where there is smoke?

Authors: Roubinian NH; Kanias T

Transfusion. 2019 08;59(8):2485-2488.

PubMed abstract

Building consensus: steps toward standardised haemovigilance reporting

Authors: Roubinian N; Kleinman S

Lancet Haematol. 2019 07;6(7):e339-e340. Epub 2019-05-09.

PubMed abstract

Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients

Authors: Edgren G; Lee C; Roubinian NH; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Group; et al.

JAMA. 2019 06 11;321(22):2183-2192.

PubMed abstract

Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study

Authors: Roubinian NH; Murphy EL; Mark DG; Triulzi DJ; Carson JL; Lee C; Kipnis P; Kleinman S; Liu VX; Escobar GJ

Ann Intern Med. 2019 01 01;170(1):80.

PubMed abstract

TACO and TRALI: biology, risk factors, and prevention strategies

Authors: Roubinian N

Hosp Pediatr. 2019 05;9(5):340-347.

PubMed abstract

Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload

Authors: Roubinian NH; National Heart, Lung, and Blood Institute (NHLBI) Recipient Epidemiology and Donor Evaluation Study-III (REDS-III); et al.

Crit Care Med. 2018 04;46(4):577-585.

PubMed abstract

Statistical Caution in Big Data Approaches to Transfusion Medicine Research

Authors: Roubinian N; Brambilla D; Murphy EL

JAMA Intern Med. 2017 06 01;177(6):860-861.

PubMed abstract

Adjusting the Focus on Transfusion-associated Circulatory Overload

Authors: Roubinian N; Murphy EL

Anesthesiology. 2017 03;126(3):363-365.

PubMed abstract

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