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Ousseny Zerbo, PhD


Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 267-7529 (phone)

Ousseny Zerbo, PhD, is a Research Scientist in the Vaccine Study Center at Kaiser Permanente Northern California Division of Research. His research interest is in maternal vaccination during pregnancy and early childhood health outcomes, vaccine uptake, safety and effectiveness. He recently received a career development grant from the National Institutes of Health to study the effectiveness of maternal influenza vaccination during pregnancy and infant risk of influenza. He also studies risk factors associated with autism spectrum disorders. Prior to joining the Vaccine Study Center, he completed post-doctoral training in the Autism Research Program at the Division of Research. He received his PhD in epidemiology from the University of California Davis and his bachelor's degree in biological science and teaching credential from the University of Ouagadougou, Burkina Faso, West Africa. 

Current Position(s):

  • Research Scientist I

Section Affiliations:

Primary Research Interests:

  • Vaccine safety and effectiveness
  • Autism spectrum disorder

Related Website(s):

COVID-19 Vaccine Effectiveness in Pregnant Women and their Infants

The overall goals are to: Determine COVID-19 vaccine effectiveness in pregnant women for preventing laboratory-confirmed COVID-19 and hospitalization for COVID-19 using real-world clinical data; Determine effectiveness of maternal COVID-19 vaccination during pregnancy for infants 0-12 months for outcomes of laboratory-confirmed COVID-19, and hospitalization for COVID-19, and determine whether effectiveness varies by trimester of vaccination; Estimate COVID-19 vaccination rates among pregnant women and identify sociodemographic, geographic clusters and other factors associated with being unvaccinated.
Investigator: Zerbo, Ousseny
Funder: National Institute of Allergy and Infectious Diseases

Analysis to evaluate the effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhea

The goal of this study is to use electronic medical records from 2016 to 2020 to evaluate the protective effect of MenB-4C vaccine against gonococcal infections among 16- to 23-year-old persons.
Investigator: Zerbo, Ousseny
Funder: Centers for Disease Control and Prevention

Effect of Maternal Influenza Vaccination during Pregnancy on Risk of Infant Influenza

This project has three major aims: 1) to examine whether influenza vaccination during pregnancy prevents influenza and other respiratory infections in infants aged 0 to 12 months, with a sub-aim to examine the effect of vaccine timing during pregnancy on these outcomes; 2) to evaluate the effect of maternal influenza vaccination during pregnancy on the effectiveness of influenza vaccine administered to infants; and 3) to examine whether influenza non-vaccination during pregnancy clusters geographically, and determine if those clusters are associated with influenza and influenza-like illnesses during pregnancy.
Investigator: Zerbo, Ousseny
Funder: National Institute of Allergy and Infectious Diseases

Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder

Author(s): Zerbo O; Qian Y; Yoshida C; Fireman BH; Klein NP; Croen LA

JAMA Pediatr. 2016 Nov 28.

PubMed abstract

Effectiveness of 2-Dose Vaccination with mRNA COVID-19 Vaccines Against COVID-19-Associated Hospitalizations Among Immunocompromised Adults - Nine States, January-September 2021

Author(s): Embi PJ; Klein NP; Fireman B; Zerbo O; DeSilva MB; et al.

MMWR Morb Mortal Wkly Rep. 2021 Nov 05;70(44):1553-1559. Epub 2021-11-05.

PubMed abstract

Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19-Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity - Nine States, January-September 2021

Author(s): Bozio CH; Klein NP; Fireman B; Zerbo O; Stenehjem E; et al.

MMWR Morb Mortal Wkly Rep. 2021 Nov 05;70(44):1539-1544. Epub 2021-11-05.

PubMed abstract

Lessons from a mature acellular pertussis vaccination program and strategies to overcome suboptimal vaccine effectiveness

Author(s): Zerbo O; Fireman B; Klein NP

Expert Rev Vaccines. 2021 Sep 24.

PubMed abstract

Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings

Author(s): Thompson MG; Fireman B; Zerbo O; Klein NP; et al.

N Engl J Med. 2021 Sep 08.

PubMed abstract

COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California

Author(s): Ames JL; Ferrara A; Avalos LA; Badon SE; Hedderson MM; Kuzniewicz MW; Young-Wolff KC; Zerbo O; Zhu Y; Croen LA; et al.

PLoS One. 2021;16(9):e0256891. Epub 2021-09-03.

PubMed abstract

Surveillance for Adverse Events After COVID-19 mRNA Vaccination

Author(s): Klein NP; Fireman B; Zerbo O; Weintraub ES; et al.

JAMA. 2021 Sep 03.

PubMed abstract

Population-based assessment of risks for severe COVID-19 disease outcomes

Author(s): Zerbo O; Lewis N; Fireman B; Goddard K; Skarbinski J; Sejvar JJ; Azziz-Baumgartner E; Klein NP

Influenza Other Respir Viruses. 2021 Aug 25.

PubMed abstract

COVID-19 Vaccination Coverage Among Insured Persons Aged ≥16 Years, by Race/Ethnicity and Other Selected Characteristics - Eight Integrated Health Care Organizations, United States, December 14, 2020-May 15, 2021

Author(s): Pingali C; Klein NP; Fireman B; Zerbo O; Patel SA; et al.

MMWR Morb Mortal Wkly Rep. 2021 Jul 16;70(28):985-990. Epub 2021-07-16.

PubMed abstract

COVID-19 Vaccination Coverage Among Pregnant Women During Pregnancy - Eight Integrated Health Care Organizations, United States, December 14, 2020-May 8, 2021

Author(s): Razzaghi H; Zerbo O; Patel SA; et al.

MMWR Morb Mortal Wkly Rep. 2021 Jun 18;70(24):895-899. Epub 2021-06-18.

PubMed abstract

Vaccine Safety Datalink infrastructure enhancements for evaluating the safety of maternal vaccination

Author(s): Naleway AL; Klein NP; Zerbo O; Kharbanda EO; et al.

Ther Adv Drug Saf. 2021;12:20420986211021233. Epub 2021-06-14.

PubMed abstract

Genetic associations with a fever after measles-containing vaccines

Author(s): Klein NP; Zerbo O; Goddard K; Wang W; Fohner AE; Wiesner A; Shokoohi V; Coller J; Bok K; Gans HA

Hum Vaccin Immunother. 2020 Dec 22:1-7.

PubMed abstract

Individual and Neighborhood Factors Associated with Failure to Vaccinate against Influenza during Pregnancy

Author(s): Zerbo O; Ray T; Zhang L; Goddard K; Fireman B; Adams A; Omer S; Kulldorff M; Klein NP

Am J Epidemiol. 2020 Jul 31.

PubMed abstract

Risk for Subdeltoid Bursitis After Influenza Vaccination: A Population-Based Cohort Study

Author(s): Hesse EM; Navarro RA; Daley MF; Getahun D; Henninger ML; Jackson LA; Nordin J; Olson SC; Zerbo O; Zheng C; Duffy J

Ann Intern Med. 2020 Jun 23.

PubMed abstract

Identification and description of mumps cases in a non-outbreak setting and evaluation of the effectiveness of mumps-containing vaccines over time

Author(s): Zerbo O; Modaressi S; Glanternik JR; Goddard K; Ross P; Lewis N; Klein NP

Hum Vaccin Immunother. 2020 May 13:1-5.

PubMed abstract

Order of Live and Inactivated Vaccines and Risk of Non-vaccine-targeted Infections in US Children 11-23 Months of Age

Author(s): Newcomer SR; Zerbo O; Glanz JM; et al.

Pediatr Infect Dis J. 2020 Mar;39(3):247-253.

PubMed abstract

Vaccine effectiveness of cell-culture relative to egg-based inactivated influenza vaccine during the 2017-18 influenza season

Author(s): Klein NP; Fireman B; Goddard K; Zerbo O; Asher J; Zhou J; King J; Lewis N

PLoS ONE. 2020;15(2):e0229279. Epub 2020-02-26.

PubMed abstract

Trivalent inactivated influenza vaccine (IIV3) during pregnancy and six-month infant development

Author(s): Avalos LA; Ferber J; Zerbo O; Odouli R; Li DK; et al.

Vaccine. 2020 Feb 28;38(10):2326-2332. Epub 2020-02-05.

PubMed abstract

Parental Risk Factors for Fever in their Children 7-10 Days After the First Dose of Measles-Containing Vaccines

Author(s): Zerbo O; Modaressi S; Goddard K; Lewis E; Bok K; Gans H; Klein NP

Hum Vaccin Immunother. 2019 Oct 04.

PubMed abstract

Infection and Fever in Pregnancy and Autism Spectrum Disorders: Findings from the Study to Explore Early Development

Author(s): Croen LA; Qian Y; Zerbo O; Ames JL; et al.

Autism Res. 2019 Jul 17.

PubMed abstract

An Exploratory Examination of Neonatal Cytokines and Chemokines as Predictors of Autism Risk: The Early Markers for Autism Study

Author(s): Heuer LS; Croen LA; Jones KL; Yoshida CK; Hansen RL; Yolken R; Zerbo O; DeLorenze G; Kharrazi M; Ashwood P; Van de Water J

Biol Psychiatry. 2019 May 15.

PubMed abstract

Acellular Pertussis Vaccine Effectiveness Over Time

Author(s): Zerbo O; Bartlett J; Goddard K; Fireman B; Lewis E; Klein NP

Pediatrics. 2019 Jun 10.

PubMed abstract

Factors Affecting Vaccination in Children and Their Siblings After Autism Spectrum Disorder Diagnosis-Reply

Author(s): Zerbo O; Klein NP

JAMA Pediatr. 2018 Aug 06.

PubMed abstract

Vaccination Patterns in Children After Autism Spectrum Disorder Diagnosis and in Their Younger Siblings

Author(s): Zerbo O; Modaressi S; Goddard K; Lewis E; Fireman BH; Klein NP; et al.

JAMA Pediatr. 2018 Mar 26.

PubMed abstract

Association Between Estimated Cumulative Vaccine Antigen Exposure Through the First 23 Months of Life and Non-Vaccine-Targeted Infections From 24 Through 47 Months of Age

Author(s): Glanz JM; Newcomer SR; Daley MF; DeStefano F; Groom HC; Jackson ML; Lewin BJ; McCarthy NL; McClure DL; Narwaney KJ; Nordin JD; Zerbo O

JAMA. 2018 03 06;319(9):906-913.

PubMed abstract

Use of acellular pertussis vaccines in the United States: can we do better?

Author(s): Klein NP; Zerbo O

Expert Rev Vaccines. 2017 Oct 20:1-5.

PubMed abstract

No association between influenza vaccination during pregnancy and adverse birth outcomes

Author(s): Zerbo O; Modaressi S; Chan B; Goddard K; Lewis N; Bok K; Fireman B; Klein NP; Baxter R

Vaccine. 2017 May 31;35(24):3186-3190. Epub 2017-05-05.

PubMed abstract

Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder

Author(s): Zerbo O; Qian Y; Yoshida C; Fireman BH; Klein NP; Croen LA

JAMA Pediatr. 2016 Nov 28.

PubMed abstract

​Kaiser Permanente Northern California pregnancy database: Description and proof of concept study

Author(s): Zerbo O; Chan B; Goddard K; Lewis N; Bok K; Klein NP; Baxter R;

​Vaccine. 2016 Nov 4;34(46):5519-5523. doi: 10.1016/j.vaccine.2016.10.006. Epub 2016 Oct 7.

PubMed abstract

Polychlorinated Biphenyl and Organochlorine Pesticide Concentrations in Maternal Mid-Pregnancy Serum Samples: Association with Autism Spectrum Disorder and Intellectual Disability

Author(s): Lyall K; Croen LA; Sj?din A; Yoshida CK; Zerbo O; Kharrazi M; Windham GC

Environ Health Perspect. 2016 Aug 23.

PubMed abstract

Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation

Author(s): Jones KL; Croen LA; Yoshida CK; Heuer L; Hansen R; Zerbo O; DeLorenze GN; Kharrazi M; Yolken R; Ashwood P; Van de Water J

Mol Psychiatry. 2016 May 24.

PubMed abstract

​Maternal mid-pregnancy C-reactive protein and risk of autism spectrum disorders: the early markers for autism study

Author(s): Zerbo O; Traglia M; Yoshida C; Heuer LS; Ashwood P; Delorenze GN; Hansen RL; Kharrazi M; Van de Water J; Yolken RH; Weiss LA; Croen LA;

​Transl Psychiatry. 2016 Apr 19;6:e783. doi: 10.1038/tp.2016.46.

PubMed abstract

The health status of adults on the autism spectrum

Author(s): Croen LA; Zerbo O; Qian Y; Massolo ML; Rich S; Sidney S; Kripke C;

PubMed abstract

A Study of Physician Knowledge and Experience with Autism in Adults in a Large Integrated Healthcare System

Author(s): Zerbo O; Massolo ML; Qian Y; Croen LA

J Autism Dev Disord. 2015 Sep 3.

PubMed abstract

Immune mediated conditions in autism spectrum disorders

Author(s): Zerbo O; Leong A; Barcellos L; Bernal P; Fireman B; Croen LA

Brain Behav Immun. 2015 May;46:232-6. Epub 2015-02-11.

PubMed abstract

Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study

Author(s): Zerbo O; Yoshida C; Grether JK; Van de Water J; Ashwood P; Delorenze GN; Hansen RL; Kharrazi M; Croen LA

J Neuroinflammation. 2014;11:113. Epub 2014-06-20.

PubMed abstract

Maternal Infection During Pregnancy and Autism Spectrum Disorders

Author(s): Zerbo O; Qian Y; Yoshida C; Grether JK; Van de Water J; Croen LA

J Autism Dev Disord. 2013 Dec 24.

PubMed abstract

A genome-wide survey of transgenerational genetic effects in autism

Author(s): Tsang KM; Croen LA; Torres AR; Kharrazi M; Delorenze GN; Windham GC; Yoshida CK; Zerbo O; Weiss LA

PLoS ONE. 2013;8(10):e76978. Epub 2013-10-24.

PubMed abstract

Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) study

Author(s): Zerbo O; Iosif AM; Walker C; Ozonoff S; Hansen RL; Hertz-Picciotto I;

​J Autism Dev Disord. 2013 Jan;43(1):25-33. doi: 10.1007/s10803-012-1540-x.

PubMed abstract

​Month of conception and risk of autism

Author(s): Zerbo O; Iosif AM; Delwiche L; Walker C; Hertz-Picciotto I;

​Epidemiology. 2011 Jul;22(4):469-75. doi: 10.1097/EDE.0b013e31821d0b53.

PubMed abstract