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Yeyi Zhu, PhD

yeyi.zhu@kp.org

Kaiser Permanente Researcher Profiles

Zhu, Yeyi

Yeyi Zhu, PhD, is a Research Scientist III at Kaiser Permanente Northern California Division of Research and Associate Adjunct Professor at Department of Epidemiology and Biostatistics, University of California, San Francisco. She received her bachelor’s degree in Biological Sciences from Fudan University, Shanghai, China, and master’s degree in Statistics and PhD in Nutritional Epidemiology from The University of Texas at Austin. Dr. Zhu completed her postdoctoral training with an intramural research training award at Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH.

In 2016, Dr. Zhu joined the Division of Research to expand the scale and generalizability of her work to real-world health care settings serving over 4 million members. Dr. Zhu’s research interests are at the interface of disease etiology and prevention strategies in the arena of women’s and children’s health across the lifespan. She has conducted etiological investigations to identify pre-diagnostic markers for gestational diabetes and risk factors for its progression to type 2 diabetes, as well as the respective underlying pathophysiological mechanisms. She has also investigated the impact of high-dimensional in-utero air pollution exposures (i.e., criteria air pollutants and air toxics) on adverse pregnancy and birth outcomes. Furthermore, she applies a life course approach to examine the developmental origins of cardiometabolic impairments of offspring exposed to nonoptimal intrauterine environment by integrating ‘omics technologies, high-dimensional electronic health records, and “big data” analytics tools. Her research aims to inform upstream preventive strategies to interrupt the vicious intergenerational cycle of obesity and diabetes and its related comorbidities across the lifespan. Dr. Zhu’s research is sponsored by grants from the National Institute of Diabetes and Digestive and Kidney Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and institutional funding.

Current Positions

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California
  • Associate Adjunct Professor, Department of Epidemiology and Biostatistics, University of California, San Francisco

Section Affiliations

Primary Research Interests

  • Developmental origins of metabolic impairments
  • Gestational diabetes and type 2 diabetes
  • Fetal growth and childhood obesity
  • Nutrition in critical windows of development
  • Prenatal exposure to environmental hazards

Related Websites

Studies

Elucidating the High and Heterogenous Risk of Gestational Diabetes among Asian Americans: An Integrative Approach of Metabolomics, Lifestyles and Social Determinants

This study will leverage the California Alpha-fetoprotein Screening Program (CA-AFSP) and the Pregnancy Environment and Lifestyle Study (PETALS) to identify metabolites and pathways among Asian American racial/ethnic subpopulations with gestational diabetes in the CA-AFSP discovery set; validate the shared and unique metabolites and pathways for gestational diabetes among all and each racial and ethnic subpopulation in PETALS; and examine the role of lifestyle factors and social determinants of health in the racial and ethnic specific GDM-related metabolites and pathways.

Investigator: Zhu, Yeyi

Funder: National Institute on Minority Health and Health Disparities

Preconception and Prenatal Health Impacting Factors and Child Health

The study will recruit a diverse cohort of 1,800 pregnant individuals, the conceiving partner, their resulting child, and will follow all of them at multiple visits after the child is born to contribute to the Environmental influences on Child Health Outcomes (ECHO) Program. We will examine the role of in utero exposure to psychological distress and substance use on child growth, adiposity, obesity, and neurodevelopment (ND) and the extent to which prenatal lifestyle factors and neighborhood factors may mitigate these associations. We will clarify the joint effects of maternal prenatal dietary patterns and the 24-hour movement and child growth, obesity, and ND and whether metabolomic signatures prenatally, at birth, and postnatally mediate these associations. There will also be a preconception pilot study to explore the role of maternal and paternal lifestyle factors on infant health to identify critical time periods to intervene on to prevent upstream risk factors for childhood obesity and ND.

Investigator: Hedderson, Monique; Zhu, Yeyi; Avalos, Lyndsay

Funder: National Institutes of Health

Blood Pressure, Obesity, and Diabetes in Relation to Perinatal and Postpartum Complications

By leveraging the KPNC Gestational diabetes and Glucose Tolerance Registry, which includes rich data on blood glucose levels, obesity, gestational weight gain, we will add blood pressure levels for the earliest years to evaluate the individual and joint impact of pregnancy blood pressure, blood glucose, and obesity categories on perinatal complications and examine whether associations of pregnancy blood pressure, blood glucose, and obesity categories with perinatal complications vary by race/ethnicity in the pregnant women in the KPNC integrated health care system.

Investigator: Zhu, Yeyi

Funder: National Heart, Lung, and Blood Institute

Fetal Programming of Growth and Obesity: A Metabolomics Approach

This proposal uses a novel holistic framework that leverages both targeted and untargeted metabolomics approach, electronic health records data, and bioinformatics analytics to investigate the mechanisms by which the in-utero environment may infer risk of fetal growth extremes and altered infant growth trajectories and excess adiposity. It will also explore metabolomic signatures for maternal dietary factors during pregnancy, as a means to objectively capture dietary exposures in utero.

Investigator: Zhu, Yeyi

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Investigation of Prevalence of and Barriers to Achieving Optimal Glycemic Control among Women with Gestational Diabetes

This project aims to demonstrate that sufficient, high quality glycemic control data are available for investigating the determinants of and barriers to glycemic control among women with gestational diabetes in a cohort of 30,000 women at Kaiser Permanente Northern California from 2007-2017.

Investigator: Zhu, Yeyi

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Risk Prediction of Gestational Diabetes Treatment Modalities Utilizing Clinical and Laboratory Data in the EHR

This study aims to utilize data from the Kaiser Permanente Northern California Gestational Diabetes and Pregnancy Glucose Tolerance Registry for a cohort of 25,000 women diagnosed with gestational diabetes. The goal is to determine whether clinical and laboratory factors can be utilized to predict treatment modalities for this disease (medical nutrition therapy, glyburide, or insulin).

Investigator: Zhu, Yeyi

Funder: National Institutes of Health

Publications

Gestational Diabetes Mellitus and Subsequent Risks of Diabetes and Cardiovascular Diseases: the Life Course Perspective and Implications of Racial Disparities

Authors: Chen, Liwei;Zhu, Yeyi

Curr Diab Rep. 2024 Nov;24(11):244-255. Epub 2024-09-04.

PubMed abstract

Neighborhood Food Access in Early Life and Trajectories of Child Body Mass Index and Obesity

Authors: Aris, Izzuddin M;Hedderson, Monique M;Zhu, Yeyi;Ferrara, Assiamira;Chehab, Rana F;ECHO Cohort Consortium,;et al.

JAMA Pediatr. 2024 Sep 16.

PubMed abstract

Prenatal Cannabis Use and Maternal Pregnancy Outcomes

Authors: Young-Wolff, Kelly C;Adams, Sara R;Alexeeff, Stacey E;Zhu, Yeyi;Chojolan, Edwin;Slama, Natalie E;Does, Monique B;Silver, Lynn D;Ansley, Deborah;Castellanos, Carley L;Avalos, Lyndsay A

JAMA Intern Med. 2024 Sep 01;184(9):1083-1093.

PubMed abstract

Racial, Ethnic, and Geographic Differences in Vaginal Birth After Cesarean Delivery in the US, 2011-2021

Authors: Chehab, Rana F;Ferrara, Assiamira;Grobman, William A;Greenberg, Mara B;Ngo, Amanda L;Wang, Emily Z;Zhu, Yeyi

JAMA Netw Open. 2024 May 01;7(5):e2412100. Epub 2024-05-01.

PubMed abstract

Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study

Authors: Aris, Izzuddin M;Ferrara, Assiamira;Zhu, Yeyi;Chehab, Rana F;ECHO Awardees and Cohorts,;et al.

Am J Clin Nutr. 2024 Mar 01.

PubMed abstract

Prevalence of maternal hyperglycemic subtypes by race/ethnicity and associations between these subtypes with adverse pregnancy outcomes: Findings from a large retrospective multi-ethnic cohort in the United States

Authors: Liu, Xinyue;Janzen, Carla;Zhu, Yeyi;Seamans, Marissa;Fei, Zhe;Nianogo, Roch;Chen, Liwei

Diabetes Res Clin Pract. 2024 Mar;209:111576. Epub 2024-02-14.

PubMed abstract

Metabolomic data presents challenges for epidemiological meta-analysis: a case study of childhood body mass index from the ECHO consortium

Authors: Prince, Nicole;Zhu, Yeyi;Kelly, Rachel S;et al.

Metabolomics. 2024 Jan 24;20(1):16. Epub 2024-01-24.

PubMed abstract

Maternal Pre-Pregnancy BMI, Breastfeeding, and Child BMI

Authors: Shipp, Gayle M;Zhu, Yeyi;Ferrara, Assiamira;program collaborators for Environmental influences on Child Health Outcomes,;et al.

Pediatrics. 2024 Jan 01;153(1).

PubMed abstract

Gestational diabetes mellitus and risk of neurodevelopmental disorders in young offspring: does the risk differ by race and ethnicity?

Authors: Liu, Xinyue;Zhu, Yeyi;Seamans, Marissa;Nianogo, Roch;Janzen, Carla;Fei, Zhe;Chen, Liwei

Am J Obstet Gynecol MFM. 2024 Jan;6(1):101217. Epub 2023-11-07.

PubMed abstract

Associations of Organophosphate Ester Flame Retardant Exposures during Pregnancy with Gestational Duration and Fetal Growth: The Environmental influences on Child Health Outcomes (ECHO) Program

Authors: Oh, Jiwon;Ames, Jennifer L;Croen, Lisa A;Ferrara, Assiamira;Zhu, Yeyi;program collaborators for Environmental influences on Child Health Outcomes,;et al.

Environ Health Perspect. 2024 Jan;132(1):17004. Epub 2024-01-24.

PubMed abstract

Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis

Authors: Francis, Ellen C;Zhu, Yeyi;ADA/EASD PMDI,;et al.

Commun Med (Lond). 2023 Dec 18;3(1):185. Epub 2023-12-18.

PubMed abstract

Longitudinal lipidomic profiles during pregnancy and associations with neonatal anthropometry: findings from a multiracial cohort

Authors: Song, Yiqing;Lu, Ruijin;Yu, Guoqi;Rahman, Mohammad L;Chen, Liwei;Zhu, Yeiyi;Tsai, Michael Y;Fiehn, Oliver;Chen, Zhen;Zhang, Cuilin

EBioMedicine. 2023 Dec;98:104881. Epub 2023-11-24.

PubMed abstract

Intrinsic motivation for physical activity, healthy eating, and self-weighing in association with corresponding behaviors in early pregnancy

Authors: Brown, Susan D;Kiernan, Michaela;Ehrlich, Samantha F;Zhu, Yeyi;Hedderson, Monique M;Daredia, Saher;Feng, Juanran;Millman, Andrea;Quesenberry, Charles P;Ferrara, Assiamira

Prev Med Rep. 2023 Dec;36:102456. Epub 2023-10-04.

PubMed abstract

Opportunities for Examining Child Health Impacts of Early-Life Nutrition in the ECHO Program: Maternal and Child Dietary Intake Data from Pregnancy to Adolescence

Authors: Bragg, Megan G;Hedderson, Monique M;Zhu, Yeyi;program collaborators for Environmental influences on Child Health Outcomes,;et al.

Curr Dev Nutr. 2023 Nov;7(11):102019. Epub 2023-10-23.

PubMed abstract

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Authors: Tobias, Deirdre K;Zhu, Yeyi;Franks, Paul W;et al.

Nat Med. 2023 Oct;29(10):2438-2457. Epub 2023-10-05.

PubMed abstract

PFAS concentrations in early and mid-pregnancy and risk of gestational diabetes mellitus in a nested case-control study within the ethnically and racially diverse PETALS cohort

Authors: Peterson, Alicia K;Zhu, Yeyi;Fuller, Sophia;Feng, Juanran;Alexeeff, Stacey;Mitro, Susanna D;Kannan, Kurunthachalam;Robinson, Morgan;Padula, Amy;Ferrara, Assiamira

BMC Pregnancy Childbirth. 2023 Sep 13;23(1):657. Epub 2023-09-13.

PubMed abstract

Prenatal depression and risk of child autism-related traits among participants in the Environmental influences on Child Health Outcomes program

Authors: Avalos, Lyndsay A;Gao, Xingyu;Cioffi, Camille C;Goldson, Brandon;Wright, Rosalind J;Zhu, Yeyi;Program Collaborators for Environmental influences on Child Health Outcomes,;et al.

Autism Res. 2023 Sep;16(9):1825-1835. Epub 2023-08-01.

PubMed abstract

Prenatal Health Care Outcomes Before and During the COVID-19 Pandemic Among Pregnant Individuals and Their Newborns in an Integrated US Health System

Authors: Ferrara, Assiamira;Greenberg, Mara;Zhu, Yeyi;Avalos, Lyndsay A;Ngo, Amanda;Shan, Jun;Hedderson, Monique M;Quesenberry, Charles P

JAMA Netw Open. 2023 Jul 03;6(7):e2324011. Epub 2023-07-03.

PubMed abstract

Prenatal exposure to per- and polyfluoroalkyl substances and childhood autism-related outcomes

Authors: Ames, Jennifer L; Avalos, Lyndsay A; Croen, Lisa A; Ferrara, Assiamira; Hedderson, Monique M; Zhu, Yeyi; program collaborators for Environmental influences on Child Health Outcomes,; et al.

Epidemiology. 2023 May 01;34(3):450-459. Epub 2023-04-03.

PubMed abstract

In utero metabolomic signatures of refined grains intake and risk of gestational diabetes: A metabolome-wide association study

Authors: Chehab, Rana F; Ferrara, Assiamira; Zheng, Siwen; Barupal, Dinesh K; Ngo, Amanda L; Chen, Liwei; Fiehn, Oliver; Zhu, Yeyi

Am J Clin Nutr. 2023 Apr;117(4):731-740. Epub 2023-02-11.

PubMed abstract

Birth Outcomes in Relation to Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Stress in the Environmental Influences on Child Health Outcomes (ECHO) Program

Authors: Padula, Amy M; Ferrara, Assiamira; Zhu, Yeyi; program collaborators for Environmental influences on Child Health Outcomes,; et al.

Environ Health Perspect. 2023 Mar;131(3):37006. Epub 2023-03-15.

PubMed abstract

Metabolomic biomarkers of the mediterranean diet in pregnant individuals: A prospective study

Authors: Chen, Liwei; Zhu, Yeyi; Zhang, Cuilin; et al.

Clin Nutr. 2023 Mar;42(3):384-393. Epub 2023-01-14.

PubMed abstract

Dietary Quality Indices in Early Pregnancy and Rate of Gestational Weight Gain among a Prospective Multi-Racial and Ethnic Cohort

Authors: Liu, Emily F; Zhu, Yeyi; Ferrara, Assiamira; Hedderson, Monique M

Nutrients. 2023 Feb 06;15(4). Epub 2023-02-06.

PubMed abstract

Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021

Authors: Hedderson, Monique M; Zhu, Yeyi; Ferrara, Assiamira; Environmental Influences on Child Health Outcomes Program,; et al.

JAMA Netw Open. 2023 Feb 01;6(2):e2256157. Epub 2023-02-01.

PubMed abstract

Indoor and outdoor air pollution and couple fecundability: a systematic review

Authors: Siegel, Eva L; Zhu, Yeyi; Kahn, Linda G; et al.

Hum Reprod Update. 2023 Jan 05;29(1):45-70.

PubMed abstract

Habitual coffee consumption and subsequent risk of type 2 diabetes in individuals with a history of gestational diabetes – a prospective study

Authors: Yang, Jiaxi; Zhu, Yeyi; Zhang, Cuilin; et al.

Am J Clin Nutr. 2022 Dec 19;116(6):1693-1703.

PubMed abstract

Physical activity and individual plasma phospholipid saturated fatty acids in pregnancy, a longitudinal study among a multiracial/multiethnic cohort in the United States

Authors: Liu, Xinyue; Zhu, Yeyi; Zhang, Cuilin; et al.

Am J Clin Nutr. 2022 Dec 19;116(6):1729-1737.

PubMed abstract

Associations of Neighborhood Opportunity and Social Vulnerability With Trajectories of Childhood Body Mass Index and Obesity Among US Children

Authors: Aris, Izzuddin M; Ferrara, Assiamira; Zhu, Yeyi; Program Collaborators for Environmental Influences on Child Health Outcomes,; et al.

JAMA Netw Open. 2022 Dec 01;5(12):e2247957. Epub 2022-12-01.

PubMed abstract

Plasma Phospholipids Monounsaturated Fatty Acids and Gestational Diabetes Mellitus: a Longitudinal Study in the NICHD Fetal Growth Studies-Singleton Cohort

Authors: Tsoi, Kit Ying; Zhu, Yeyi; Wu, Jing; Sun, Qi; Hinkle, Stefanie N; Li, Ling-Jun; Chen, Zhen; Weir, Natalie L; Tsai, Michael Y; Ma, Ronald Cw; Zhang, Cuilin

Diabetes. 2022 Dec 01;71(12):2707-2715.

PubMed abstract

Urinary Phenols in Early to Mid-Pregnancy and Risk of Gestational Diabetes: A Longitudinal Study in a Multiracial Cohort

Authors: Zhu, Yeyi; Hedderson, Monique M; Calafat, Antonia M; Alexeeff, Stacey E; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

Diabetes. 2022 Dec 01;71(12):2539-2551.

PubMed abstract

Association between Quality of Maternal Prenatal Food Source and Preparation and Breastfeeding Duration in the Environmental Influences on Child Health Outcome (ECHO) Program

Authors: Zimmerman, Emily; Zhu, Yeyi; On Behalf Of Program Collaborators For Environmental Influences On Child Health Outcomes,; et al.

Nutrients. 2022 Nov 21;14(22). Epub 2022-11-21.

PubMed abstract

Gestational diabetes mellitus, prenatal maternal depression, and risk for postpartum depression: an Environmental influences on Child Health Outcomes (ECHO) Study

Authors: Shuffrey, Lauren C; Hedderson, Monique M; Zhu, Yeyi; program collaborators for Environmental influences on Child Health Outcomes,; et al.

BMC Pregnancy Childbirth. 2022 Oct 08;22(1):758. Epub 2022-10-08.

PubMed abstract

Development and validation of prediction models for gestational diabetes treatment modality using supervised machine learning: a population-based cohort study

Authors: Liao, Lauren D; Ferrara, Assiamira; Greenberg, Mara B; Ngo, Amanda L; Feng, Juanran; Zhang, Zhenhua; Bradshaw, Patrick T; Hubbard, Alan E; Zhu, Yeyi

BMC Med. 2022 09 15;20(1):307. Epub 2022-09-15.

PubMed abstract

Racial/ethnic disparities in subjective sleep duration, sleep quality, and sleep disturbances during pregnancy: an ECHO study

Authors: Lucchini, Maristella; Wright, Rosalind J; Environmental influences on Child Health Outcomes; et al.

Sleep. 2022 Sep 08;45(9).

PubMed abstract

Glycemic Control Trajectories and Risk of Perinatal Complications Among Individuals With Gestational Diabetes

Authors: Chehab, Rana F; Ferrara, Assiamira; Greenberg, Mara B; Ngo, Amanda L; Feng, Juanran; Zhu, Yeyi

JAMA Netw Open. 2022 Sep 01;5(9):e2233955. Epub 2022-09-01.

PubMed abstract

Predictive Metabolomic Markers in Early to Mid-Pregnancy for Gestational Diabetes: A Prospective Test and Validation Study

Authors: Zhu, Yeyi; Barupal, Dinesh K; Ngo, Amanda L; Quesenberry, Charles P; Feng, Juanran; Fiehn, Oliver; Ferrara, Assiamira

Diabetes. 2022 08 01;71(8):1807-1817.

PubMed abstract

Coping strategies for COVID-19 pandemic-related stress and mental health during pregnancy

Authors: Badon, Sylvia E; Croen, Lisa A; Ferrara, Assiamira; Ames, Jennifer L; Hedderson, Monique M; Young-Wolff, Kelly C; Zhu, Yeyi; Avalos, Lyndsay A

J Affect Disord. 2022 Jul 15;309:309-313. Epub 2022-04-28.

PubMed abstract

Associations between antenatal corticosteroid exposure and neurodevelopment in infants

Authors: Tao, Shiyao; Zhu, Yeyi; CNBC Study Group,; et al.

Am J Obstet Gynecol. 2022 Jun 03.

PubMed abstract

Uptake of guideline-recommended postpartum diabetes screening among diverse women with gestational diabetes: associations with patient factors in an integrated health system in USA

Authors: Brown, Susan D; Hedderson, Monique M; Zhu, Yeyi; Tsai, Ai-Lin; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

BMJ Open Diabetes Res Care. 2022 06;10(3).

PubMed abstract

Perinatal Complications in Individuals in California With or Without SARS-CoV-2 Infection During Pregnancy

Authors: Ferrara, Assiamira; Hedderson, Monique M; Zhu, Yeyi; Avalos, Lyndsay A; Kuzniewicz, Michael W; Myers, Laura C; Ngo, Amanda L; Gunderson, Erica P; Ritchie, Jenna L; Quesenberry, Charles P; Greenberg, Mara

JAMA Intern Med. 2022 05 01;182(5):503-512.

PubMed abstract

Cumulative Lactation and Clinical Metabolic Outcomes at Mid-Life among Women with a History of Gestational Diabetes

Authors: Wander, Pandora L; Zhu, Yeyi; Zhang, Cuilin; et al.

Nutrients. 2022 Feb 03;14(3). Epub 2022-02-03.

PubMed abstract

Longitudinal Associations of Plasma Phospholipid Fatty Acids in Pregnancy with Neonatal Anthropometry: Results from the NICHD Fetal Growth Studies-Singleton Cohort

Authors: Wang E; Zhu Y; Chehab RF; Wu J; Hinkle SN; Weir NL; Bremer AA; Yang J; Chen Z; Tsai MY; Zhang C

Nutrients. 2022 Jan 29;14(3). Epub 2022-01-29.

PubMed abstract

A longitudinal study on associations of moderate-to-vigorous physical activity with plasma monounsaturated fatty acids in pregnancy

Authors: Xia, Tong; Chen, Liwei; Fei, Zhe; Liu, Xinyue; Dai, Jin; Hinkle, Stefanie N; Zhu, Yeyi; Wu, Jing; Weir, Natalie L; Tsai, Michael Y; Zhang, Cuilin

Front Nutr. 2022;9:983418. Epub 2022-10-24.

PubMed abstract

Associations of COVID-19-Related Health, Healthcare and Economic Factors With Prenatal Depression and Anxiety

Authors: Avalos, Lyndsay A; Nance, Nerissa; Badon, Sylvia E; Young-Wolff, Kelly; Ames, Jennifer; Zhu, Yeyi; Hedderson, Monique M; Ferrara, Assiamira; Zerbo, Ousseny; Greenberg, Mara; Croen, Lisa A

Int J Public Health. 2022;67:1604433. Epub 2022-05-04.

PubMed abstract

Contributions of COVID-19 Pandemic-Related Stressors to Racial and Ethnic Disparities in Mental Health During Pregnancy

Authors: Avalos, Lyndsay A; Nance, Nerissa; Zhu, Yeyi; Croen, Lisa A; Young-Wolff, Kelly C; Zerbo, Ousseny; Hedderson, Monique M; Ferrara, Assiamira; Ames, Jennifer L; Badon, Sylvia E

Front Psychiatry. 2022;13:837659. Epub 2022-03-14.

PubMed abstract

The Role of Childhood Asthma in Obesity Development: A Nationwide U.S. Multi-cohort Study

Authors: Stratakis, Nikos; Ferrara, Assiamira; Zhu, Yeyi; program collaborators for Environmental influences on Child Health Outcomes,; et al.

Epidemiology. 2022 01 01;33(1):131-140.

PubMed abstract

Plasma Acylcarnitines during Pregnancy and Neonatal Anthropometry: A Longitudinal Study in a Multiracial Cohort

Authors: Song, Yiqing; Zhu, Yeyi; Zhang, Cuilin; et al.

Metabolites. 2021 Dec 17;11(12). Epub 2021-12-17.

PubMed abstract

Are you what you eat? Through the lens of prepregnancy plant-based diets and risk of gestational diabetes

Authors: Zhu, Yeyi

Am J Clin Nutr. 2021 12 01;114(6):1892-1893.

PubMed abstract

Changes of Plasma Phospholipid Fatty Acids Profiles in Pregnancy in Relation to the Diagnosis and Treatment of Gestational Diabetes Mellitus

Authors: Li, Lingjun; Zhu, Yeyi; Wu, Jing; Hinkle, Stefanie N; Tobias, Deirdre K; Ma, Ronald C W; Weir, Natalie L; Tsai, Michael Y; Zhang, Cuilin

Clin Chem. 2021 Nov 26;67(12):1660-1675.

PubMed abstract

Disparities in Risks of Inadequate and Excessive Intake of Micronutrients during Pregnancy

Authors: Sauder, Katherine A; Avalos, Lyndsay A; Zhu, Yeyi; Breton, Carrie V; Program Collaborators for Environmental influences on Child Health Outcomes (ECHO),; et al.

J Nutr. 2021 11 02;151(11):3555-3569.

PubMed abstract

Maternal Proinflammatory Adipokines Throughout Pregnancy and Neonatal Size and Body Composition: A Prospective Study

Authors: Francis, Ellen C; Li, Mengying; Hinkle, Stefanie N; Chen, Jinbo; Wu, Jing; Zhu, Yeyi; Cao, Haiming; Tsai, Michael Y; Chen, Liwei; Zhang, Cuilin

Curr Dev Nutr. 2021 Oct;5(10):nzab113. Epub 2021-09-07.

PubMed abstract

Associations of household food insufficiency with childhood depression and anxiety: a nationwide cross-sectional study in the USA

Authors: Zheng, Siwen; Ngo, Amanda L; Forman, Michele R; Barcellos, Anna L; Liao, Lauren; Ferrara, Assiamira; Zhu, Yeyi

BMJ Open. 2021 09 07;11(9):e054263. Epub 2021-09-07.

PubMed abstract

Longitudinal Plasma Metabolomics Profile in Pregnancy-A Study in an Ethnically Diverse U.S. Pregnancy Cohort

Authors: Mitro, Susanna D; Zhu, Yeyi; Zhang, Cuilin; et al.

Nutrients. 2021 Sep 01;13(9). Epub 2021-09-01.

PubMed abstract

Association of Habitual Alcohol Consumption With Long-term Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes

Authors: Hinkle, Stefanie N; Zhu, Yeyi; Zhang, Cuilin; et al.

JAMA Netw Open. 2021 09 01;4(9):e2124669. Epub 2021-09-01.

PubMed abstract

Healthy preconception and early-pregnancy lifestyle and risk of preterm birth: a prospective cohort study

Authors: Zhu, Yeyi; Hedderson, Monique M; Brown, Susan D; Badon, Sylvia E; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

Am J Clin Nutr. 2021 08 02;114(2):813-821.

PubMed abstract

A longitudinal study of plasma acylcarnitines throughout pregnancy and associations with risk of gestational diabetes mellitus

Authors: Lin, Yuan; Wu, Jing; Zhu, Yeyi; Hinkle, Stefanie N; Rawal, Shristi; Liang, Liming; Weir, Natalie L; Tsai, Michael Y; Zhang, Cuilin

Clin Nutr. 2021 08;40(8):4863-4870. Epub 2021-07-10.

PubMed abstract

Household mold, pesticide use, and childhood asthma: A nationwide study in the U.S

Authors: Xiao, Siyuan; Ngo, Amanda L; Mendola, Pauline; Bates, Michael N; Barcellos, Anna L; Ferrara, Assiamira; Zhu, Yeyi

Int J Hyg Environ Health. 2021 04;233:113694. Epub 2021-02-06.

PubMed abstract

Plasma lipidomics profile in pregnancy and gestational diabetes risk: a prospective study in a multiracial/ethnic cohort

Authors: Rahman, Mohammad L; Feng, Yen-Chen A; Fiehn, Oliver; Albert, Paul S; Tsai, Michael Y; Zhu, Yeyi; Wang, Xiaobin; Tekola-Ayele, Fasil; Liang, Liming; Zhang, Cuilin

BMJ Open Diabetes Res Care. 2021 03;9(1).

PubMed abstract

Persistent organic pollutants and couple fecundability: a systematic review

Authors: Kahn, Linda G; Harley, Kim G; Siegel, Eva L; Zhu, Yeyi; Factor-Litvak, Pam; Porucznik, Christina A; Klein-Fedyshin, Michele; Hipwell, Alison E; program collaborators for Environmental Influences on Child Health Outcomes Program,

Hum Reprod Update. 2021 02 19;27(2):339-366.

PubMed abstract

COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California

Authors: Ames, Jennifer L; Ferrara, Assiamira; Avalos, Lyndsay A; Badon, Sylvia E; Greenberg, Mara B; Hedderson, Monique M; Kuzniewicz, Michael W; Young-Wolff, Kelly C; Zerbo, Ousseny; Zhu, Yeyi; Croen, Lisa A; et al.

PLoS One. 2021;16(9):e0256891. Epub 2021-09-03.

PubMed abstract

Plasma Phospholipid n-3/n-6 Polyunsaturated Fatty Acids and Desaturase Activities in Relation to Moderate-to-Vigorous Physical Activity through Pregnancy: A Longitudinal Study within the NICHD Fetal Growth Studies

Authors: Chen, Liwei; Zhu, Yeyi; Zhang, Cuilin; et al.

Nutrients. 2020 Nov 19;12(11). Epub 2020-11-19.

PubMed abstract

Nut Consumption and Renal Function Among Women With a History of Gestational Diabetes

Authors: Ajjarapu AS; Zhu Y; Zhang C; et al.

J Ren Nutr. 2020 09;30(5):415-422. Epub 2020-01-17.

PubMed abstract

Adipokines in early and mid-pregnancy and subsequent risk of gestational diabetes: a longitudinal study in a multiracial cohort

Authors: Francis, Ellen C; Zhu, Yeyi; Zhang, Cuilin; et al.

BMJ Open Diabetes Res Care. 2020 07;8(1).

PubMed abstract

Prenatal Depression and Diet Quality During Pregnancy

Authors: Avalos LA; Caan B; Nance N; Zhu Y; Li DK; Quesenberry C; Hyde RJ; Hedderson MM

J Acad Nutr Diet. 2020 06;120(6):972-984. Epub 2020-02-13.

PubMed abstract

Food insecurity and the extremes of childhood weight: defining windows of vulnerability

Authors: Zhu Y; Mangini LD; Hayward MD; Forman MR

Int J Epidemiol. 2020 04 01;49(2):519-527.

PubMed abstract

Understanding childhood obesity in the US: the NIH environmental influences on child health outcomes (ECHO) program

Authors: Tylavsky FA; Ferrara A; Hedderson MM; Zhu Y; Trasande L; et al.

Int J Obes (Lond). 2020 03;44(3):617-627. Epub 2019-10-24.

PubMed abstract

Sex Hormone-binding Globulin, Cardiometabolic Biomarkers, and Gestational Diabetes: A Longitudinal Study and Meta-analysis

Authors: Li, Meng-Ying; Rawal, Shristi; Hinkle, Stefanie N; Zhu, Ye-Yi; Tekola-Ayele, Fasil; Tsai, Michael Y; Liu, Si-Min; Zhang, Cui-Lin

Matern Fetal Med. 2020 Jan;2(1):2-9. Epub 2020-01-24.

PubMed abstract

Plasma Prolactin and Progesterone Levels and the Risk of Gestational Diabetes: A Prospective and Longitudinal Study in a Multiracial Cohort

Authors: Li M; Song Y; Rawal S; Hinkle SN; Zhu Y; Tekola-Ayele F; Ferrara A; Tsai MY; Zhang C

Front Endocrinol (Lausanne). 2020;11:83. Epub 2020-02-27.

PubMed abstract

Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research

Authors: Pellizzari ED; Woodruff TJ; Boyles RR; Kannan K; Beamer PI; Buckley JP; Wang A; Zhu Y; Bennett DH; (Environmental influences on Child Health Outcomes)

Environ Health Perspect. 2019 12;127(12):126001. Epub 2019-12-18.

PubMed abstract

Racial/Ethnic Disparities in the Prevalence of Diabetes and Prediabetes by BMI: Patient Outcomes Research To Advance Learning (PORTAL) Multisite Cohort of Adults in the U.S

Authors: Zhu Y; Ferrara A; et al.

Diabetes Care. 2019 12;42(12):2211-2219. Epub 2019-09-19.

PubMed abstract

A Prospective Study of Leukocyte Telomere Length and Risk of Gestational Diabetes in a Multiracial Cohort

Authors: Lin Y; Zhu Y; Wu J; Hinkle SN; Rawal S; Han J; Weir NL; Tsai MY; Zhang C

Epidemiology. 2019 11;30 Suppl 2:S10-S16.

PubMed abstract

Plasma phospholipid n-3 and n-6 polyunsaturated fatty acids in relation to cardiometabolic markers and gestational diabetes: A longitudinal study within the prospective NICHD Fetal Growth Studies

Authors: Zhu Y; Li M; Rahman ML; Hinkle SN; Wu J; Weir NL; Lin Y; Yang H; Tsai MY; Ferrara A; Zhang C

PLoS Med. 2019 09;16(9):e1002910. Epub 2019-09-13.

PubMed abstract

A prospective study of artificially sweetened beverage intake and cardiometabolic health among women at high risk

Authors: Hinkle SN; Zhu Y; Zhang C; et al.

Am J Clin Nutr. 2019 07 01;110(1):221-232.

PubMed abstract

Poor diet quality in pregnancy is associated with increased risk of excess fetal growth: a prospective multi-racial/ethnic cohort study

Authors: Zhu Y; Hedderson MM; Sridhar S; Xu F; Feng J; Ferrara A

Int J Gynaecol Obstet. 2020 Jan;148 Suppl 1:42-58.

PubMed abstract

Timing of household food insecurity exposures and asthma in a cohort of US school-aged children

Authors: Mangini LD; Hayward MD; Zhu Y; Dong Y; Forman MR

BMJ Open. 2019 02 22;8(11):e021683. Epub 2019-02-22.

PubMed abstract

Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus

Authors: Gadgil MD; Ehrlich SF; Zhu Y; Brown SD; Hedderson MM; Crites Y; Ferrara A

J Womens Health (Larchmt). 2019 02;28(2):178-184. Epub 2018-10-30.

PubMed abstract

Weight estimation among multi-racial/ethnic infants and children aged 0-5·9 years in the USA: simple tools for a critical measure

Authors: Zhu Y; Hernandez LM; Dong Y; Himes JH; Caulfield LE; Kerver JM; Arab L; Voss P; Hirschfeld S; Forman MR

Public Health Nutr. 2019 01;22(1):147-156. Epub 2018-10-18.

PubMed abstract

Central Obesity Increases the Risk of Gestational Diabetes Partially Through Increasing Insulin Resistance

Authors: Zhu Y; Hedderson MM; Quesenberry CP; Feng J; Ferrara A

Obesity (Silver Spring). 2018 Nov 21.

PubMed abstract

Longitudinal Maternal Vitamin D Status during Pregnancy Is Associated with Neonatal Anthropometric Measures

Authors: Francis EC; Hinkle SN; Song Y; Rawal S; Donnelly SR; Zhu Y; Chen L; Zhang C

Nutrients. 2018 Nov 02;10(11). Epub 2018-11-02.

PubMed abstract

Omega 3 polyunsaturated fatty acids and healthy ageing

Authors: Zhu Y; Ferrara A; Forman MR

BMJ. 2018 10 17;363:k4263. Epub 2018-10-17.

PubMed abstract

A Pre-Pregnancy Biomarker Risk Score Improves Prediction of Future Gestational Diabetes

Authors: Badon SE; Zhu Y; Sridhar SB; Xu F; Lee C; Ehrlich SF; Quesenberry CP; Hedderson MM

J Endocr Soc. 2018 Oct 01;2(10):1158-1169. Epub 2018-09-13.

PubMed abstract

Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy

Authors: Rawal S; Zhu Y; Zhang C; et al.

Diabetes Care. 2018 07;41(7):1378-1384. Epub 2018-05-04.

PubMed abstract

A Longitudinal Study of Thyroid Markers across Pregnancy and the Risk of Gestational Diabetes

Authors: Rawal S; Zhu Y; Zhang C; et al.

J Clin Endocrinol Metab. 2018 Jun 07.

PubMed abstract

A prospective and longitudinal study of plasma phospholipid saturated fatty acid profile in relation to cardiometabolic biomarkers and the risk of gestational diabetes

Authors: Zhu Y; Tsai MY; Sun Q; Hinkle SN; Rawal S; Mendola P; Ferrara A; Albert PS; Zhang C

Am J Clin Nutr. 2018 Jun 01;107(6):1017-1026.

PubMed abstract

Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study

Authors: Bao W; Dar S; Zhu Y; Wu J; Rawal S; Li S; Weir NL; Tsai MY; Zhang C

J Diabetes. 2018 Jun;10(6):487-495. Epub 2017-09-29.

PubMed abstract

Acute Associations between Outdoor Temperature and Premature Rupture of Membranes

Authors: Ha S; Liu D; Zhu Y; Sherman S; Mendola P

Epidemiology. 2018 03;29(2):175-182.

PubMed abstract

Liver Enzymes in Early to Mid-pregnancy, Insulin Resistance, and Gestational Diabetes Risk: A Longitudinal Analysis

Authors: Zhu Y; Hedderson MM; Quesenberry CP; Feng J; Ferrara A

Front Endocrinol (Lausanne). 2018;9:581. Epub 2018-10-02.

PubMed abstract

Offspring risk of obesity in childhood, adolescence and adulthood in relation to gestational diabetes mellitus: a sex-specific association

Authors: Li S; Zhu Y; Yeung E; Chavarro JE; Yuan C; Field AE; Missmer SA; Mills JL; Hu FB; Zhang C

Int J Epidemiol. 2017 10 01;46(5):1533-1541.

PubMed abstract

Spontaneous and indicated preterm delivery risk is increased among overweight and obese women without prepregnancy chronic disease

Authors: Kim SS; Mendola P; Zhu Y; Hwang BS; Grantz KL

BJOG. 2017 Oct;124(11):1708-1716. Epub 2017-04-01.

PubMed abstract

Validation of Self-Reported Diagnosis of Gestational Diabetes at Six Weeks Postpartum

Authors: Hinkle SN; Rawal S; Zhu Y; Grewal J; Albert PS; Zhang C

Epidemiology. 2017 Sep;28(5):747-752.

PubMed abstract

Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth

Authors: Mendola P; Ha S; Pollack AZ; Zhu Y; Seeni I; Kim SS; Sherman S; Liu D

Int J Environ Res Public Health. 2017 07 06;14(7). Epub 2017-07-06.

PubMed abstract

Maternal dietary intakes of refined grains during pregnancy and growth through the first 7 y of life among children born to women with gestational diabetes

Authors: Zhu Y; Zhang C; et al.

Am J Clin Nutr. 2017 Jul;106(1):96-104. Epub 2017-06-07.

PubMed abstract

Maternal consumption of artificially sweetened beverages during pregnancy, and offspring growth through 7 years of age: a prospective cohort study

Authors: Zhu Y; Zhang C; et al.

Int J Epidemiol. 2017 Jun 06.

PubMed abstract

​Ambient air pollution and risk of gestational hypertension

Authors: Zhu Y; Zhang C; Liu D; Ha S; Kim SS; Pollack A; Mendola P;

​Am J Epidemiol. 2017 May 4. doi: 10.1093/aje/kwx097. [Epub ahead of print]

PubMed abstract

​Ambient temperature and air quality in relation to small for gestational age and term low birthweight.

Authors: Ha S; Zhu Y; Liu D; Sherman S; Mendola P;

Environ Res. 2017 May;155:394-400. doi: 10.1016/j.envres.2017.02.021. Epub 2017 Mar 1.

PubMed abstract

The Pregnancy Environment and Lifestyle Study (PETALS): a population-based longitudinal multi-racial birth cohort

Authors: Zhu Y; Hedderson MM; Feng J; Mevi AA; Ferrara A

BMC Pregnancy Childbirth. 2017 04 17;17(1):122. Epub 2017-04-17.

PubMed abstract

​A longitudinal study of sleep duration in pregnancy and subsequent risk of gestational diabetes: findings from a prospective, multiracial cohort.

Authors: Rawal S; Hinkle SN; Zhu Y; Albert PS; Zhang C;

​Am J Obstet Gynecol. 2017 Apr;216(4):399.e1-399.e8. doi: 10.1016/j.ajog.2016.11.1051. Epub 2016 Dec 9.

PubMed abstract

Ambient Temperature and Early Delivery of Singleton Pregnancies.

Authors: Ha S; Liu D; Zhu Y; Kim SS; Sherman S; Mendola P.

​Environ Health Perspect. 2017 Mar;125(3):453-459. doi: 10.1289/EHP97. Epub 2016 Aug 31.

PubMed abstract

Racial/ethnic differences in preterm perinatal outcomes.

Authors: Wallace ME; Mendola P; Kim SS; Epps N; Chen Z; Smarr M; Hinkle SN; Zhu Y; Grantz KL;

​Am J Obstet Gynecol. 2017 Mar;216(3):306.e1-306.e12. doi: 10.1016/j.ajog.2016.11.1026. Epub 2016 Nov 16.

PubMed abstract

​A longitudinal study of iron status during pregnancy and the risk of gestational diabetes: findings from a prospective, multiracial cohort.

Authors: Rawal S; Hinkle SN; Bao W; Zhu Y; Grewal J; Albert PS; Weir NL; Tsai MY; Zhang C;

​Diabetologia. 2017 Feb;60(2):249-257. doi: 10.1007/s00125-016-4149-3. Epub 2016 Nov 10.

PubMed abstract

Proximity to major roadways and prospectively-measured time-to-pregnancy and infertility.

Authors: Mendola P; Sundaram R; Louis GMB; Sun L; Wallace ME; Smarr MM; Sherman S; Zhu Y; Ying Q; Liu D;

​Sci Total Environ. 2017 Jan 15;576:172-177. doi: 10.1016/j.scitotenv.2016.10.038. Epub 2016 Oct 23.

PubMed abstract

​A longitudinal study of depression and gestational diabetes in pregnancy and the postpartum period

Authors: Hinkle SN; Buck Louis GM; Rawal S; Zhu Y; Albert PS; Zhang C

​​Diabetologia. 2016 Dec;59(12):2594-2602. Epub 2016 Sep 19.

PubMed abstract

​Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort

Authors: Zhu Y; Mendola P; Albert PS; Bao W; Hinkle SN; Tsai MY; Zhang C;

​Diabetes. 2016 Nov;65(11):3495-3504. Epub 2016 Jul 28.

PubMed abstract

Obstetric and Neonatal Risks Among Obese Women Without Chronic Disease.

Authors: Kim SS; Zhu Y; Grantz KL; Hinkle SN; Chen Z; Wallace ME; Smarr MM; Epps NM; Mendola P

Obstet Gynecol. 2016 Jul;128(1):104-12. doi: 10.1097/AOG.0000000000001465.

PubMed abstract

​Exposure to Ambient Air Pollution and Premature Rupture of Membranes.

Authors: Wallace ME; Grantz KL; Liu D; Zhu Y; Kim SS; Mendola P

Am J Epidemiol. 2016 Jun 15;183(12):1114-21. doi: 10.1093/aje/kwv284. Epub 2016 May 17.

PubMed abstract

Dietary Patterns and the Risk of Hypertension Among Women With a History of Gestational Diabetes Mellitus; A Prospective Cohort Study.

Authors: Li S; Zhu Y; Chavarro JE; Bao W; Tobias DK; Ley SH; Forman JP; Liu A; Mills J; Bowers K; Strøm M; Hansen S; Hu FB; Zhang C

​Hypertension. 2016 Jun;67(6):1157-65. doi: 10.1161/HYPERTENSIONAHA.115.06747. Epub 2016 Apr 18.

PubMed abstract

Age at Menarche and Risk of Gestational Diabetes Mellitus; A Prospective Cohort Study Among 27,482 Women.

Authors: Chen L; Li S; He C; Zhu Y; Buck Louis GM; Yeung E; Hu FB; Zhang C

Diabetes Care. 2016 Mar;39(3):469-71. doi: 10.2337/dc15-2011. Epub 2016 Jan 26.

PubMed abstract

​Predictive Models for Characterizing Disparities in Exclusive Breastfeeding Performance in a Multi-ethnic Population in the US.

Authors: Zhu Y; Hernandez LM; Mueller P; Dong Y; Hirschfeld S; Forman MR;

Matern Child Health J. 2016 Feb;20(2):398-407. doi: 10.1007/s10995-015-1838-3.

PubMed abstract

​​Growth and obesity through the first 7 years of life in association with levels of maternal glycemia during pregnancy: a prospective cohort study

Authors: Zhu Y; Olsen SF; Mendola P; Yeung EH; Vaag A; Bowers K; Liu A; Bao W; Li S; Madsen C; Grunnet LG; Granström C; Hansen S; Martin K; Chavarro JE; Hu FB; Langhoff-Roos J; Damm P; Zhang C;

​Am J Clin Nutr. 2016 Mar;103(3):794-800. doi: 10.3945/ajcn.115.121780. Epub 2016 Jan 27.

PubMed abstract

Low Carbohydrate-Diet Scores and Long-term Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus; A Prospective Cohort Study.

Authors: Bao W; Li S; Chavarro JE; Tobias DK; Zhu Y; Hu FB; Zhang C

Diabetes Care. 2016 Jan;39(1):43-9. doi: 10.2337/dc15-1642. Epub 2015 Nov 17.

PubMed abstract

​Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: A Global Perspective

Authors: Zhu Y; Zhang C;

​Curr Diab Rep. 2016 Jan;16(1):7. doi: 10.1007/s11892-015-0699-x.

PubMed abstract

Longer breastfeeding duration reduces the positive relationships among gestational weight gain, birth weight and childhood anthropometrics.

Authors: Zhu Y; Hernandez LM; Dong Y; Himes JH; Hirschfeld S; Forman MR

J Epidemiol Community Health. 2015 Jul;69(7):632-8. doi: 10.1136/jech-2014-204794. Epub 2015 Feb 13.

PubMed abstract

Maternal ambient air pollution exposure preconception and during early gestation and offspring congenital orofacial defects.

Authors: Zhu Y; Zhang C; Liu D; Grantz KL; Wallace M; Mendola P

Environ Res. 2015 Jul;140:714-20. doi: 10.1016/j.envres.2015.06.002. Epub 2015 Jun 20.

PubMed abstract

Arm span and ulnar length are reliable and accurate estimates of recumbent length and height in a multiethnic population of infants and children under 6 years of age.

Authors: Forman MR; Zhu Y; Hernandez LM; Himes JH; Dong Y; Danish RK; James KE; Caulfield LE; Kerver JM; Arab L; Voss P; Hale DE; Kanafani N; Hirschfeld S

J Nutr. 2014 Sep;144(9):1480-7. doi: 10.3945/jn.114.194340. Epub 2014 Jul 16.

PubMed abstract

Data Acquisition and Preprocessing in Studies on Humans: What Is Not Taught in Statistics Classes?

Authors: Zhu Y; Hernandez LM; Mueller P; Dong Y; Forman MR

Am Stat. 2013;67(4):235-241.

PubMed abstract

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