Asgari, Maryam M.
Research interests include prevention and treatment of skin cancer.
Survey of Dermatologic Procedures in Transgender Adults
Dermatologists have the opportunity to provide medically necessary procedures, including laser hair removal, to transgender patients for gender affirmation. Further…
Hydrochlorothiazide and risk of melanoma subtypes
Hydrochlorothiazide (HCTZ), a common diuretic known to be photosensitizing and previously associated with non-melanoma skin cancer, was recently reported to…
Identification of genetic loci and pathways underlying hidradenitis suppurativa risk
Hidradenitis suppurativa (also named: acne inversa) is a chronic inflammatory skin condition that causes painful lumps to form under the…
Ten-Year Follow-up of Persons With Sun-Damaged Skin Associated With Subsequent Development of Cutaneous Squamous Cell Carcinoma
Risk of cutaneous squamous cell carcinoma (cSCC) after the diagnosis of actinic keratosis (AK) has not been studied during long…
Time-to-event analysis when the event is defined on a finite time interval
Acute graft-versus-host disease (GVHD) is a frequent complication following hematopoietic cell transplantation (HCT). Research on risk factors for acute GVHD…
Neonatal jaundice in association with autism spectrum disorder and developmental disorder
To examine the association between neonatal jaundice and autism spectrum disorder (ASD) and non-ASD developmental disorder (DD). We analyzed data…
Genetic ancestry does not explain increased atopic dermatitis susceptibility or worse disease control among African American subjects in 2 large US cohorts
Atopic dermatitis (AD) is more common among African American children. Whether there are racial/ethnic difference among adults with AD and…
Comparative Effectiveness Study of Face-to-Face and Teledermatology Workflows for Diagnosing Skin Cancer
The effectiveness and value of teledermatology and face-to-face workflows for diagnosing lesions are not adequately understood. We compared the risks…
Development of an algorithm to detect methotrexate wrong frequency error using computerized health care data
We validated an algorithm to detect frequency errors in computerized healthcare data and estimated the incidence of these errors in…
PQ3 Cutaneous Squamous Cell Carcinoma: Integrating Germline and Somatic Alterations that Underlie Tumor Progression
The goal of this proposal is to compare tumor versus normal samples of cutaneous squamous cell carcinoma in a large…
Long-term effectiveness of zoster vaccine live for postherpetic neuralgia prevention
Postherpetic neuralgia (PHN) occurs in 5-30% of individuals with herpes zoster (HZ) and is characterized by long-lasting pain. Zoster vaccine…
Comparative effectiveness of treatment of actinic keratosis with topical fluorouracil and imiquimod in the prevention of keratinocyte carcinoma: a cohort study
The effectiveness of 5-fluorouracil compared with that of imiquimod for preventing keratinocyte carcinoma is unknown. To compare the effectiveness of…
Investigating the Effects of KIR and HLA Gene Polymorphisms on Psoriasis
The goal of this project is to investigate the effects of genetic polymorphisms in the KIR and HLA genes on…
Comparative Effectiveness of Virtual Care in Dermatology for Diagnosing Rash
The benefit of teledermatology for triaging skin rashes is not adequately understood. The study will assess how implementation of teledermatology…
Atopic Dermatitis Standing Cohort Using a Cohort of Kaiser Permanente Northern California Members
A cohort study of Kaiser Permanente Northern California patients with moderate-to-severe atopic dermatitis (AD) will be used to estimate baseline…
A Prediction Tool to Facilitate Risk-Stratified Screening for Squamous Cell Skin Cancer
Cutaneous squamous cell cancers (cSCCs) present an under-recognized health issue among non-Hispanic whites, one that is likely to increase as…
Photosensitizing Antihypertensive Drug Use and Risk of Cutaneous Squamous Cell Carcinoma
Many antihypertensive drugs (ADs) are photosensitizing, heightening reactivity of the skin to sunlight. Photosensitizing ADs have been associated with lip…
Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma.
Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with genetic susceptibility loci identified in recent genome-wide association studies…
Cutaneous Melanoma Risk among People with HIV in the United States and Canada
Cutaneous melanoma incidence may be modestly elevated in people with HIV (PWH) vs. people without HIV. However, little is known…
Common mitochondrial haplogroups and cutaneous squamous cell carcinoma risk
Background: Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in United States, and its incidence is substantially…
Risk Adjustment for Hospital Characteristics Reduces Unexplained Hospital Variation in Pressure Injury Risk
Research investigating risk factors for hospital-acquired pressure injury (HAPI) has primarily focused on the characteristics of patients and nursing staff.…
Eleven loci with new reproducible genetic associations with allergic disease risk
A recent genome-wide association study (GWAS) identified 99 loci that contain genetic risk variants shared between asthma, hay fever and…
Association of Inflammatory Markers with Disease Progression in Patients with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors
We investigated the effect of inflammatory biomarkers (neutrophil, platelet, and lymphocyte counts) on risk of progression in patients with metastatic…
Susceptibility loci associated cutaneous squamous cell carcinoma invasiveness
Genome-wide association studies have identified genetic loci associated with cutaneous squamous cell carcinoma (cSCC) risk, but single-nucleotide polymorphism associations with…
A real-world, community-based cohort study comparing the effectiveness of topical fluoruracil vs. topical imiquimod for the treatment of actinic keratosis
The most widely used topical agents for the field-based treatment of multiple actinic keratoses (AKs) are 5-fluorouracil and imiquimod, but…
Patient-Oriented Research and Mentoring Program in Dermatologic Diseases
This study aims to perform an internally validated genome-wide association study of actinic keratoses (AKs) in a group of patients…
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the same individuals, partly because of…
Serious infections among a large cohort of subjects with systemically treated psoriasis
Biologic therapy is effective for treatment of moderate-to-severe psoriasis but may be associated with an increased risk for serious infection.…
Prognostics factors and survival in acral lentiginous melanoma
Acral lentiginous melanoma (ALM) is a rare melanoma subtype that disproportionately afflicts people of colour. ALMs have a worse prognosis…
Providers’ Experiences with a Melanoma Web-Based Course: a Discussion on Barriers and Intentions
Primary care visits provide an opportunity for skin examinations with the potential to reduce melanoma mortality. The INFORMED (INternet curriculum…
Temporal Trends in Satellite-Derived Erythemal UVB and Implications for Ambient Sun Exposure Assessment.
Ultraviolet radiation (UVR) has been associated with various health outcomes, including skin cancers, vitamin D insufficiency, and multiple sclerosis. Measurement…
A Database Cohort Study to Assess the Risk of Developing non-Melanoma Skin Cancer in Adult Patients with Atopic Dermatitis Exposed to Topical Calcineurin Inhibitor
The primary objective of this study is to assess the long-term risk of developing melanoma in adult subjects aged 40…
Use of sildenafil or other phosphodiesterase inhibitors and risk of melanoma
Phosphodiesterase 5A inhibitors (PDEIs), a common treatment for erectile dysfunction, were recently linked to an increased risk of melanoma. We…
Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): A case series of 8 patients highlighting different clinical manifestations
Paraneoplastic syndromes (PNS) are commonly associated with neuroendocrine cancers, such as small cell lung cancer. We examined the association of…
Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma
We report a genome-wide association study of cutaneous squamous cell carcinoma conducted among non-Hispanic white members of the Kaiser Permanente…
Voriconazole Exposure and Risk of Cutaneous Squamous Cell Carcinoma, Aspergillus Colonization, Invasive Aspergillosis and Death in Lung Transplant Recipients
Voriconazole is a triazole antifungal used to prevent and treat invasive fungal infections after lung transplantation, but it has been…
Multiple primary melanomas among 16,570 patients with melanoma diagnosed at Kaiser Permanente Northern California, 1996 to 2011
Published rates of cutaneous multiple primary melanoma (MPM) vary widely. We examined incidence of and risk factors associated with MPMs…
Trends in Basal Cell Carcinoma Incidence and Identification of High-Risk Subgroups, 1998-2012
The incidence of basal cell carcinomas (BCCs) is increasing globally, but incidence rates in the United States are difficult to…
Sirolimus use and risk of cutaneous squamous cell carcinoma (SCC) in solid organ transplant recipients (SOTRs)
Little is known about the use of sirolimus for primary prevention of cutaneous squamous cell carcinoma (SCC) among solid organ…
Identification of Stevens-Johnson syndrome and toxic epidermal necrolysis in electronic health record databases
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) carry a high mortality risk. While identifying clinical and genetic risk factors…
Family History of Skin Cancer Is Associated With Increased Risk of Cutaneous Squamous Cell Carcinoma
The contribution of family history to cutaneous squamous cell carcinoma (SCC) risk has not been systematically quantified. To examine the…
Sun sensitivity and sunburns as related to cutaneous melanoma among populations of Spanish descent: a meta-analysis.
Few studies have examined sun sensitivity risk factors for cutaneous melanoma specifically in populations of Spanish descent. Previous searches were…
Risk factors for sun exposure during spring break among college students
In order to look at college students' behavioral practices prior to a sunny vacation (during spring break) along with their…
Sebotropic eruption associated with use of oral kava kava supplement
Supplement use is prevalent, and its use is increasing among older adults. Dermatologists need to be aware of the adverse…
CD8+ Lymphocyte Intratumoral Infiltration as a Stage-Independent Predictor of Merkel Cell Carcinoma Survival: A Population-Based Study
Intratumoral CD8+ lymphocytes (IT-CD8s) have shown promise as a prognostic indicator for Merkel cell carcinoma (MCC). We tested whether IT-CD8s…
Risk of subsequent cutaneous squamous cell carcinoma in patients with melanoma
Patients with melanoma are at increased risk for cutaneous squamous cell carcinomas (SCCs). We sought to examine the incidence of…
Comparing characteristics of melanoma cases arising in health maintenance organizations with state and national registries
Datasets from large health maintenance organizations (HMOs), particularly those with established cancer registries that report to the Surveillance, Epidemiology, and…
Effect of Host, Tumor, Diagnostic, and Treatment Variables on Outcomes in a Large Cohort With Merkel Cell Carcinoma
Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine-derived skin cancer with high rates of recurrence and associated mortality. Few…
Effects on skills and practice from a web-based skin cancer course for primary care providers
Melanoma incidence and mortality is a growing concern. Better recognition and management of skin cancer by primary care providers (PCPs)…
Incidence and Prevalence of Juvenile Idiopathic Arthritis Among Children in a Managed Care Population, 1996-2009
Few studies based in well-defined North American populations have examined the occurrence of juvenile idiopathic arthritis (JIA), and none has…
Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: The Women’s Health Initiative
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with decreased risk of gastric, colorectal, and breast cancer. However, the impact…
Validation of a large Basal cell carcinoma registry
The epidemiological study of basal cell carcinomas (BCCs) is difficult because BCCs lack distinct disease codes and are excluded from…
Developing an Interactive Web-Based Learning Program on Skin Cancer: the Learning Experiences of Clinical Educators
Web-based learning in medical education is rapidly growing. However, there are few firsthand accounts on the rationale for and development…
Vitamin D in cutaneous carcinogenesis: Part I
Skin cancer is the most common cancer in the United States. Exposure to ultraviolet radiation is a known risk factor…
Vitamin D in cutaneous carcinogenesis: Part II
The role of vitamin D in health maintenance and disease prevention in fields ranging from bone metabolism to cancer is…
The association of psoriasis with autoimmune diseases
BACKGROUND: Previous studies provide evidence that there is a greater frequency of autoimmune diseases among patients with psoriasis than in…
Association of Vitamin A and Carotenoid Intake with Melanoma Risk in a Large Prospective Cohort
Laboratory data suggest that intake of vitamin A and carotenoids may have chemopreventive benefits against melanoma, but epidemiological studies examining…
Fee Comparisons of Treatments for Nonmelanoma Skin Cancer in a Private Practice Academic Setting
OBJECTIVE: To compare fees for biopsy, treatment procedure, repair, and 2-month follow-up for nonmelanoma skin cancer (NMSC) treatments: electrodesiccation and…
Clinical, Epidemiologic, Histopathologic and Molecular Features of an Unexplained Dermopathy
BACKGROUND: Morgellons is a poorly characterized constellation of symptoms, with the primary manifestations involving the skin. We conducted an investigation…
Dermatologic care in the homeless and underserved populations: observations from the Venice Family Clinic
Dermatologic care in the homeless and impoverished urban underserved populations is rarely described despite the wide prevalence of skin concerns…
Predictors of recruited melanoma families into a behavioral intervention project
BACKGROUND: Examination of families represents an important priority in health research. In this paper we report on individual and family-level…
Needs assessment for mohs micrographic surgery
Mohs micrographic surgery (MMS) is a unique technique that can offer the highest cure rates and maximum tissue conservation in…
Needs assessment for general dermatologic surgery
This article reviews current recommendations, strength of evidence, and areas in need of further research in the surgical treatment of…
Predictors of patient satisfaction with mohs surgery: analysis of preoperative, intraoperative, and postoperative factors in a prospective cohort
OBJECTIVE: To identify preoperative, intraoperative, and postoperative variables that predict higher short- and long-term patient satisfaction with Mohs surgery. DESIGN:…
Supplement use and risk of cutaneous squamous cell carcinoma
BACKGROUND: Laboratory and epidemiologic studies suggest that certain dietary supplements may alter risk of cutaneous squamous cell carcinoma (SCC). OBJECTIVE:…
The impact of the iPLEDGE program on isotretinoin fetal exposure in an integrated health care system
BACKGROUND: Preventing fetal exposure to isotretinoin is widely acknowledged as an important safety issue. The iPLEDGE program is the latest…
Skin cancer education for primary care physicians: a systematic review of published evaluated interventions
BACKGROUND: Early detection of melanoma may provide an opportunity to positively impact melanoma mortality. Numerous skin cancer educational interventions have…
Association of tea consumption and cutaneous squamous cell carcinoma
Laboratory and epidemiologic studies suggest a protective effect of tea consumption on risk of cutaneous squamous cell carcinoma (SCC). We…
Using a family systems approach to investigate cancer risk communication within melanoma families
OBJECTIVE: The family provides an important communication nexus for information and support exchange about family cancer history, and adoption of…
High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome
OBJECTIVES: To evaluate vitamin D status in patients with basal cell nevus syndrome (BCNS) who practice photoprotection because of their…
Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma
We investigated the association between serum 25-hydroxyvitamin D (25(OH)D) levels and basal cell carcinoma (BCC) risk in a nested case-control…
Association between nonsteroidal anti-inflammatory drug use and cutaneous squamous cell carcinoma
OBJECTIVE: To examine the association between nonsteroidal anti-inflammatory drug (NSAID) use and cutaneous squamous cell carcinoma (SCC). DESIGN: Retrospective case-control…
Potential risk factors for cutaneous squamous cell carcinoma include oral contraceptives: results of a nested case-control study
Recently, a population-based case-control study observed a 60% increased odds ratio (OR) for cutaneous squamous cell carcinoma (SCC) among women…
Identification of patients with nonmelanoma skin cancer using health maintenance organization claims data
Cancer registries usually exclude nonmelanoma skin cancers (NMSC), despite the large population affected. Health maintenance organization (HMO) and health system…
Selection criteria for genetic assessment of patients with familial melanoma
Approximately 5% to 10% of melanoma may be hereditary in nature, and about 2% of melanoma can be specifically attributed…
Antioxidant supplementation and risk of incident melanomas: results of a large prospective cohort study
OBJECTIVE: To examine whether antioxidant supplement use is associated with melanoma risk in light of recently published data from the…
A cohort study of vitamin D intake and melanoma risk
Data suggest that vitamin D intake may have chemopreventive efficacy against melanoma, but there have been no published epidemiologic studies…
Statin use and risk of basal cell carcinoma
OBJECTIVE: We examined the association between statin use and basal cell carcinoma (BCC) risk. METHODS: We identified all members of…
Patient satisfaction after treatment of nonmelanoma skin cancer
BACKGROUND: Patient satisfaction is an important aspect of patient-centered care but has not been systematically studied after treatment of nonmelanoma…
A large cohort study of nonsteroidal anti-inflammatory drug use and melanoma incidence
Results of laboratory studies indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) may have chemopreventive activity and therapeutic efficacy against melanoma. However,…
Associations of psoriatic arthritis and cardiovascular conditions in a large population
Purpose: We studied the hypothesis that possibly via shared inflammatory mechanisms, psoriatic arthritis (PsA) is associated with increased prevalence of…
A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris
OBJECTIVE: To determine the incidence of abnormal laboratory test results among isotretinoin users. DESIGN: Retrospective cohort. SETTING: Comprehensive managed care…
Association of basal cell skin cancers with other cancers (United States)
BACKGROUND: Persons with basal cell skin cancer (BCSC) have shown increased risk of developing cancer at several other sites. METHODS:…
Twin studies of disease heritability based on medical records: application to acne vulgaris
Establishment of the Kaiser-Permanente Twin Registry permitted the study of disease heritability in twins based on review of the twins'…
